FGF-9 Antibody (A-4): sc-373716

FGF-9 Antibody (A-4) is a mouse monoclonal IgM antibody that detects FGF-9 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FGF-9 antibody (A-4) is available as a non-conjugated format. FGF-9 protein plays a crucial role in various biological processes, including embryonic development, tissue repair, and regulation of cell proliferation and differentiation. FGF-9 (A-4) antibody has proven particularly valuable in studying development of the central nervous system and formation of the male reproductive system. FGF-9 protein interacts with specific receptors, such as FGFR1 and FGFR2, which are essential for mediating signaling pathways. These interactions initiate downstream signaling cascades that influence cellular responses. Research using FGF-9 (A-4) monoclonal antibody can provide insights into developmental biology and potential therapeutic targets for diseases related to cell growth and differentiation.

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FGF-9 Antibody (A-4) References:

1. Up-regulation of fibroblast growth factor (FGF) 9 expression and FGF-WNT/β-catenin signaling in laser-induced wound healing.  |  Zheng, Z., et al. 2014. Wound Repair Regen. 22: 660-5. PMID: 25041895
2. Osteoblast-derived FGF9 regulates skeletal homeostasis.  |  Wang, L., et al. 2017. Bone. 98: 18-25. PMID: 28189801
3. The correlation between adiponectin and FGF9 in depression disorder.  |  Wang, XQ., et al. 2020. Brain Res. 1729: 146596. PMID: 31836511
4. FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis.  |  Shamsi, F., et al. 2020. Nat Commun. 11: 1421. PMID: 32184391
5. FGF9 promotes mouse spermatogonial stem cell proliferation mediated by p38 MAPK signalling.  |  Yang, F., et al. 2021. Cell Prolif. 54: e12933. PMID: 33107118
6. FGF9 promotes cell proliferation and tumorigenesis in TM3 mouse Leydig progenitor cells.  |  Chang, MM., et al. 2022. Am J Cancer Res. 12: 5613-5630. PMID: 36628285
7. Fgf9 promotes incisor dental epithelial stem cell survival and enamel formation.  |  Tang, L., et al. 2024. Stem Cell Res Ther. 15: 293. PMID: 39256850
8. Cordycepin Activates Autophagy to Suppress FGF9-induced TM3 Mouse Leydig Progenitor Cell Proliferation.  |  Wu, SZ., et al. 2024. Cancer Genomics Proteomics. 21: 630-644. PMID: 39467624
9. Identification of fibroblast growth factor 9 (FGF9) as a high affinity, heparin dependent ligand for FGF receptors 3 and 2 but not for FGF receptors 1 and 4.  |  Hecht, D., et al. 1995. Growth Factors. 12: 223-33. PMID: 8619928
10. Autocrine transformation by fibroblast growth factor 9 (FGF-9) and its possible participation in human oncogenesis.  |  Matsumoto-Yoshitomi, S., et al. 1997. Int J Cancer. 71: 442-50. PMID: 9139882

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FGF-9 Antibody (A-4) has 5 citations in a variety of scientific publications.

Primary antibodies like Anti-FGF-9 Antibody (A-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FGF-9 Antibody (A-4) Specifications

Alternate Product Name: FGF-9

Product Clone Name: A-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 181-208

Epitope Target: FGF-9

Epitope Species: human

Product Reactivity/Detection: precursor and mature FGF-9, FGF-16 and FGF-20

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 5 citations in various scientific publications

Available Conjugates/Forms for FGF-9 Antibody (A-4): P: Blocking Peptide

The preferred FGF-9 antibody is FGF-9 Antibody (D-8): sc-8413.