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FGF-3 Antibody (MSD 1): sc-135

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Datasheets
  • FGF-3 Antibody (MSD 1) is a mouse monoclonal IgG2a κ FGF-3 antibody, cited in 11 publications, provided at 200 µg/ml
  • raised against an int-2 synthetic peptide of mouse origin
  • FGF-3 Antibody (MSD 1) is recommended for detection of precursor and mature FGF-3 of mouse, rat and human origin by WB, IP, IF and IHC(P)
  • Anti-FGF-3 Antibody (MSD 1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FGF-3 Antibody (MSD 1). This work is in progress.
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FGF-3 Antibody (MSD 1) is a mouse monoclonal IgG2a kappa light chain antibody that detects FGF-3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. FGF-3 Antibody (MSD 1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FGF-3 plays a crucial role in embryonic development and tissue repair, primarily functioning as a signaling molecule that promotes cell proliferation and differentiation. FGF-3 is particularly important in the development of the central nervous system and the formation of various tissues, including the skin and limbs. Proper regulation of FGF-3 is essential, as dysregulation can lead to developmental disorders and contribute to the progression of certain cancers. Understanding FGF-3 interactions with other fibroblast growth factors, such as FGF-1 and FGF-2, is vital for elucidating its role in cellular signaling pathways and therapeutic applications.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

FGF-3 Antibody (MSD 1) References:

  1. Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells.  |  Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
  2. Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.  |  Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
  3. Recent developments in the cell biology of basic fibroblast growth factor.  |  Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
  4. Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.  |  Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
  5. An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.  |  Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
  6. Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus.  |  Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
  7. The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.  |  Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
  8. Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.  |  Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
  9. Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression.  |  Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

FGF-3 Antibody (MSD 1)

sc-135
200 µg/ml
$322.00

FGF-3 Antibody (MSD 1) AC

sc-135 AC
500 µg/ml, 25% agarose
$424.00

FGF-3 Antibody (MSD 1) HRP

sc-135 HRP
200 µg/ml
$322.00

FGF-3 Antibody (MSD 1) FITC

sc-135 FITC
200 µg/ml
$336.00

FGF-3 Antibody (MSD 1) PE

sc-135 PE
200 µg/ml
$349.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 488

sc-135 AF488
200 µg/ml
$364.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 546

sc-135 AF546
200 µg/ml
$364.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 594

sc-135 AF594
200 µg/ml
$364.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 647

sc-135 AF647
200 µg/ml
$364.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 680

sc-135 AF680
200 µg/ml
$364.00

FGF-3 Antibody (MSD 1) Alexa Fluor® 790

sc-135 AF790
200 µg/ml
$364.00

I am using FGF-3 (MSD 1): sc-135 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: jenniferc
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 2 out of 5 by from Worked with human recombinant FGFWorked with human recombinant FGF-3 by WB with some background. -SCBT QC
Date published: 2015-01-24
Rated 2 out of 5 by from Produced positive immunoperoxidase cytoplasmicProduced positive immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human placenta tissue. -SCBT QC
Date published: 2013-10-13
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FGF-3 Antibody (MSD 1) is rated 2.0 out of 5 by 2.
  • y_2026, m_4, d_23, h_7
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