FGF-12 Antibody (ZA-12): sc-81947

FGF-12 Antibody (ZA-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects FGF-12 of mouse, rat, and human origin by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-FGF-12 antibody (ZA-12) is available as a non-conjugated format. FGF-12 plays a crucial role in regulating neuronal development and function, particularly in the central nervous system, where FGF-12 is involved in processes such as neurogenesis and synaptic plasticity. Understanding FGF-12 function is important due to implications in various neurological disorders, making FGF-12 a potential target for therapeutic intervention. FGF-12 interacts with other fibroblast growth factors, including FGF-1 and FGF-2, which stimulate cell proliferation and differentiation across various tissue types. Such interaction highlights FGF-12 significance in growth factor signaling pathways, emphasizing relevance in both developmental biology and disease states.

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FGF-12 Antibody (ZA-12) References:

1. Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells.  |  Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
2. Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.  |  Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
3. Recent developments in the cell biology of basic fibroblast growth factor.  |  Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
4. Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.  |  Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
5. An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.  |  Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
6. Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus.  |  Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
7. The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.  |  Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
8. Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.  |  Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
9. Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression.  |  Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FGF-12 Antibody (ZA-12) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-FGF-12 Antibody (ZA-12) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FGF-12 Antibody (ZA-12) Specifications

Alternate Product Name: FGF-12

Product Clone Name: ZA-12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-182

Epitope Target: FGF-12

Epitope Species: human

Product Reactivity/Detection: FGF-12

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF, IHC(P), ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for FGF-12 Antibody (ZA-12): N/A