FBXO25 Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects FBXO25 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FBXO25 Antibody (G-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FBXO25, also known as F-box only protein 25, is a 367 amino acid protein characterized by a C-terminal F-box domain, which is essential for its role in the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex. This complex is crucial for substrate recognition and recruitment for ubiquitination, thereby regulating cellular processes such as cell cycle, immune response, signaling pathways, and developmental processes through targeted degradation of proteins like cyclins and b-catenin. FBXO25 is predominantly localized in the nucleus and interacts directly with Skp1 p19 and CUL-1, highlighting its importance in cellular regulation. Disruption of FBXO25 has been linked to X-linked mental retardation, underscoring its significance in neurodevelopmental processes.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FBXO25 Antibody (G-5) | sc-390219 | 200 µg/ml | $316.00 | |||
FBXO25 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-530097 | 200 µg Ab; 10 µg BP | $354.00 | |||
FBXO25 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-523453 | 200 µg Ab, 40 µg BP | $354.00 | |||
FBXO25 Antibody (G-5): m-IgG1 BP-HRP Bundle | sc-543868 | 200 µg Ab; 20 µg BP | $354.00 | |||
FBXO25 Antibody (G-5) AC | sc-390219 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FBXO25 Antibody (G-5) HRP | sc-390219 HRP | 200 µg/ml | $316.00 | |||
FBXO25 Antibody (G-5) FITC | sc-390219 FITC | 200 µg/ml | $330.00 | |||
FBXO25 Antibody (G-5) PE | sc-390219 PE | 200 µg/ml | $343.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 488 | sc-390219 AF488 | 200 µg/ml | $357.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 546 | sc-390219 AF546 | 200 µg/ml | $357.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 594 | sc-390219 AF594 | 200 µg/ml | $357.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 647 | sc-390219 AF647 | 200 µg/ml | $357.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 680 | sc-390219 AF680 | 200 µg/ml | $357.00 | |||
FBXO25 Antibody (G-5) Alexa Fluor® 790 | sc-390219 AF790 | 200 µg/ml | $357.00 |