FBXO18 Antibody (2353C1a): sc-81563

FBXO18 (2353C1a) is a mouse monoclonal IgG1 antibody that detects FBXO18 protein of human origin by western blotting (WB) and immunoprecipitation (IP). FBXO18 (2353C1a) antibody is available as the non-conjugated form. FBXO18 (F-box only protein 18, F-box DNA helicase 1) is a 1,043 amino acid protein encoded by the human gene FBXO18. FBXO18 belongs to the helicase family (UvrD subfamily) and contains one F-box domain. This nuclear protein is a DNA-dependent ATPase that unwinds double-stranded DNA in a 3′ to 5′ direction. FBXO18 also recognizes and binds to a variety of phosphorylated proteins and promotes their ubiquitination and degradation. FBXO18 also interacts with Skp1 in the SCF E3 ubiquitin ligase complex consisting of Skp1, CUL-1, Rbx1 and FBXO18.

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FBXO18 Antibody (2353C1a) References:

1. Non-replicative helicases at the replication fork.  |  Heller, RC. and Marians, KJ. 2007. DNA Repair (Amst). 6: 945-52. PMID: 17382604
2. UvrD controls the access of recombination proteins to blocked replication forks.  |  Lestini, R. and Michel, B. 2007. EMBO J. 26: 3804-14. PMID: 17641684
3. A multi-gene approach to differentiate papillary thyroid carcinoma from benign lesions: gene selection using support vector machines with bootstrapping.  |  Fujarewicz, K., et al. 2007. Endocr Relat Cancer. 14: 809-26. PMID: 17914110
4. Proteomic analysis of augmented immune responses in mouse by prime-and-boost immunization strategy with DNA vaccine coding HBsAg and rHBsAg protein.  |  Wang, Y., et al. 2007. Vaccine. 25: 8146-53. PMID: 18029065
5. Evolutionary conservation of plant gibberellin signalling pathway components.  |  Vandenbussche, F., et al. 2007. BMC Plant Biol. 7: 65. PMID: 18047669
6. Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis.  |  Kumar, KG., et al. 2007. J Cell Biol. 179: 935-50. PMID: 18056411
7. Characterisation of cisplatin coordination sites in cellular Escherichia coli DNA-binding proteins by combined biphasic liquid chromatography and ESI tandem mass spectrometry.  |  Will, J., et al. 2008. J Biol Inorg Chem. 13: 421-34. PMID: 18157731

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FBXO18 Antibody (2353C1a) has 10 citations in a variety of scientific publications.

Primary antibodies like Anti-FBXO18 Antibody (2353C1a) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FBXO18 Antibody (2353C1a) Specifications

Alternate Product Name: FBXO18

Product Clone Name: 2353C1a

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: FBXO18

Epitope Species: human

Product Reactivity/Detection: FBXO18

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 1.0% stabilizer protein

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for FBXO18 Antibody (2353C1a): N/A