FAM47E Antibody (H-11): sc-515364
- FAM47E Antibody (H-11) is a mouse monoclonal IgG2b κ FAM47E antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 82-99 within an internal region of FAM47E of mouse origin
- FAM47E Antibody (H-11) is recommended for detection of FAM47E of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FAM47E Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FAM47E Antibody (H-11) for WB applications. These reagents are now offered in bundles with FAM47E Antibody (H-11) (see ordering information below).
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FAM47E Antibody (H-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects FAM47E protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM47E antibody (H-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FAM47E protein, consisting of 351 amino acids, plays a crucial role in cellular processes, particularly in regulation of gene expression and cellular signaling pathways. FAM47E protein function is vital for maintaining normal cellular homeostasis and has implications in various diseases, including cancer. FAM47E gene is located on human chromosome 4, a region significant not only for genetic content but also for association with several genetic disorders, such as Huntington′s disease and achondroplasia. This chromosome is known for containing large gene deserts and has one of the lowest recombination frequencies among human chromosomes, which can impact genetic diversity and disease susceptibility. With versatile applications and critical role in cellular function, FAM47E monoclonal antibody (H-11) is an essential tool for researchers studying complexities of gene regulation and associated pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FAM47E Antibody (H-11) References:
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- Selective neuronal degeneration in Huntington's disease. | Cowan, CM. and Raymond, LA. 2006. Curr Top Dev Biol. 75: 25-71. PMID: 16984809
- Syndromic craniosynostosis: from history to hydrogen bonds. | Cunningham, ML., et al. 2007. Orthod Craniofac Res. 10: 67-81. PMID: 17552943
- Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. | Ruiz-Perez, VL., et al. 2007. Development. 134: 2903-12. PMID: 17660199
- Growth hormone analysis and treatment in Ellis-van Creveld syndrome. | Versteegh, FG., et al. 2007. Am J Med Genet A. 143A: 2113-21. PMID: 17702014
- Metabolic phenotype of methylmalonic acidemia in mice and humans: the role of skeletal muscle. | Chandler, RJ., et al. 2007. BMC Med Genet. 8: 64. PMID: 17937813
- Muenke syndrome (FGFR3-related craniosynostosis): expansion of the phenotype and review of the literature. | Doherty, ES., et al. 2007. Am J Med Genet A. 143A: 3204-15. PMID: 18000976
- Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. | Stack, EC., et al. 2007. J Neurosci. 27: 12908-15. PMID: 18032664
- Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias. | de Frutos, CA., et al. 2007. Dev Cell. 13: 872-83. PMID: 18061568
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM47E Antibody (H-11) | sc-515364 | 200 µg/ml | $316.00 | |||
FAM47E Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-525013 | 200 µg Ab, 40 µg BP | $354.00 | |||
FAM47E Antibody (H-11): m-IgG2b BP-HRP Bundle | sc-549205 | 200 µg Ab; 10 µg BP | $354.00 | |||
FAM47E Antibody (H-11) AC | sc-515364 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FAM47E Antibody (H-11) HRP | sc-515364 HRP | 200 µg/ml | $316.00 | |||
FAM47E Antibody (H-11) FITC | sc-515364 FITC | 200 µg/ml | $330.00 | |||
FAM47E Antibody (H-11) PE | sc-515364 PE | 200 µg/ml | $343.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 488 | sc-515364 AF488 | 200 µg/ml | $357.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 546 | sc-515364 AF546 | 200 µg/ml | $357.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 594 | sc-515364 AF594 | 200 µg/ml | $357.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 647 | sc-515364 AF647 | 200 µg/ml | $357.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 680 | sc-515364 AF680 | 200 µg/ml | $357.00 | |||
FAM47E Antibody (H-11) Alexa Fluor® 790 | sc-515364 AF790 | 200 µg/ml | $357.00 | |||
FAM47E (H-11) Neutralizing Peptide | sc-515364 P | 100 µg/0.5 ml | $68.00 |