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FAM163A Antibody (E-7) is a mouse monoclonal IgM antibody that detects FAM163A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FAM163A, also known as C1orf76 or neuroblastoma-derived secretory protein (NDSP), is a 167 amino acid single-pass membrane protein that plays a significant role in cellular signaling and communication, particularly in neuroblastoma, where high expression levels may serve as a marker for metastasis in bone marrow. FAM163A localization within the cell membrane facilitates interactions with other membrane proteins and receptors, thereby influencing various signaling pathways vital for cell proliferation and differentiation. The gene encoding FAM163A is located on human chromosome 1, a region spanning 260 million base pairs and containing over 3,000 genes, many implicated in various diseases, including several cancers. Aberrations in chromosome 1 are frequently observed in malignancies such as head and neck cancer, malignant melanoma, and multiple myeloma, highlighting FAM163A′s importance in cancer research and potential as a therapeutic target. Anti-FAM163A antibody (E-7) is an essential tool for researchers investigating this protein′s role in disease progression and cellular mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM163A Antibody (E-7) | sc-398152 | 200 µg/ml | $316.00 | |||
FAM163A (E-7) Neutralizing Peptide | sc-398152 P | 100 µg/0.5 ml | $68.00 |