FAM163A Antibody (G-12): sc-393821
- FAM163A Antibody (G-12) is a mouse monoclonal IgG2b κ FAM163A antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 66-89 within an internal region of FAM163A of human origin
- FAM163A Antibody (G-12) is recommended for detection of FAM163A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FAM163A Antibody (G-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for FAM163A Antibody (G-12) for WB applications. This reagent is now offered in a bundle with FAM163A Antibody (G-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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FAM163A Antibody (G-12) is a mouse monoclonal IgG2b kappa light chain antibody that detects FAM163A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM163A antibody (G-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FAM163A, also known as C1orf76 or neuroblastoma-derived secretory protein (NDSP), is a 167 amino acid single-pass membrane protein that plays a crucial role in cellular signaling and communication, particularly in neuroblastoma, where high expression levels may serve as a marker for metastasis in bone marrow. FAM163A localization in the cell membrane facilitates interactions with other membrane proteins and receptors, influencing various signaling pathways vital for cell proliferation and differentiation. FAM163A gene is located on human chromosome 1, a region spanning 260 million base pairs and containing over 3,000 genes, many associated with various diseases, including several cancers. Aberrations in chromosome 1 have been implicated in conditions such as familial adenomatous polyposis, Stickler syndrome, and multiple myeloma, highlighting FAM163A significance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FAM163A Antibody (G-12) References:
- Gaucher disease and parkinsonism: a phenotypic and genotypic characterization. | Tayebi, N., et al. 2001. Mol Genet Metab. 73: 313-21. PMID: 11509013
- Exclusion of an extracolonic disease modifier locus on chromosome 1p33-36 in a large Swiss familial adenomatous polyposis kindred. | Plasilova, M., et al. 2004. Eur J Hum Genet. 12: 365-71. PMID: 14735163
- Neuroblastoma-derived secretory protein messenger RNA levels correlate with high-risk neuroblastoma. | Vasudevan, SA., et al. 2007. J Pediatr Surg. 42: 148-52. PMID: 17208556
- Fas-associated factor 1 and Parkinson's disease. | Betarbet, R., et al. 2008. Neurobiol Dis. 31: 309-15. PMID: 18573343
- Strong evidence for a novel schizophrenia risk locus on chromosome 1p31.1 in homogeneous pedigrees from Tamil Nadu, India. | Holliday, EG., et al. 2009. Am J Psychiatry. 166: 206-15. PMID: 18829870
- Analysis of the vitreous membrane in a case of type 1 Stickler syndrome. | Yokoi, T., et al. 2009. Graefes Arch Clin Exp Ophthalmol. 247: 715-8. PMID: 19089441
- Gain of chromosome arm 1q in patients in relapse and progression of multiple myeloma. | Balcárková, J., et al. 2009. Cancer Genet Cytogenet. 192: 68-72. PMID: 19596256
- Mutation of a gene encoding a protein with extracellular matrix motifs in Usher syndrome type IIa. | Eudy, JD., et al. 1998. Science. 280: 1753-7. PMID: 9624053
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM163A Antibody (G-12) | sc-393821 | 200 µg/ml | $316.00 | |||
FAM163A Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-524103 | 200 µg Ab, 40 µg BP | $354.00 | |||
FAM163A Antibody (G-12) AC | sc-393821 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FAM163A Antibody (G-12) HRP | sc-393821 HRP | 200 µg/ml | $316.00 | |||
FAM163A Antibody (G-12) FITC | sc-393821 FITC | 200 µg/ml | $330.00 | |||
FAM163A Antibody (G-12) PE | sc-393821 PE | 200 µg/ml | $343.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 488 | sc-393821 AF488 | 200 µg/ml | $357.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 546 | sc-393821 AF546 | 200 µg/ml | $357.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 594 | sc-393821 AF594 | 200 µg/ml | $357.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 647 | sc-393821 AF647 | 200 µg/ml | $357.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 680 | sc-393821 AF680 | 200 µg/ml | $357.00 | |||
FAM163A Antibody (G-12) Alexa Fluor® 790 | sc-393821 AF790 | 200 µg/ml | $357.00 | |||
FAM163A (G-12) Neutralizing Peptide | sc-393821 P | 100 µg/0.5 ml | $68.00 |