FAM163A Antibody (B-8): sc-390936
- FAM163A Antibody (B-8) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 105-134 near the C-terminus of FAM163A of human origin
- recommended for detection of FAM163A of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and bovine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for FAM163A Antibody (B-8) for WB applications. These reagents are now offered in bundles with FAM163A Antibody (B-8) (see ordering information below).
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FAM163A Antibody (B-8) is a mouse monoclonal IgG1 antibody that detects FAM163A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FAM163A, also known as C1orf76 or neuroblastoma-derived secretory protein, is a 167 amino acid single-pass membrane protein that plays a significant role in cellular signaling and may be implicated in the progression of neuroblastoma, particularly due to its high expression in this cancer type. FAM163A′s localization within the cell membrane is crucial, as this positioning suggests a role in mediating interactions between the cell and its environment, which can influence processes such as cell adhesion, migration, and communication. The gene encoding FAM163A is located on human chromosome 1, a region densely populated with genes associated with various diseases, including several cancers. Given FAM163A′s importance in neuroblastoma metastasis, anti-FAM163A antibody (B-8) serves as a valuable tool for researchers investigating the molecular mechanisms underlying cancer progression and for developing potential therapeutic strategies.
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FAM163A Antibody (B-8) References:
- Neuroblastoma-derived secretory protein is a novel secreted factor overexpressed in neuroblastoma. | Vasudevan, SA., et al. 2009. Mol Cancer Ther. 8: 2478-89. PMID: 19671756
- Borderline personality disorder and childhood maltreatment: a genome-wide methylation analysis. | Prados, J., et al. 2015. Genes Brain Behav. 14: 177-88. PMID: 25612291
- Sequential Fractionation Strategy Identifies Three Missing Proteins in the Mitochondrial Proteome of Commonly Used Cell Lines. | Ronci, M., et al. 2018. J Proteome Res. 17: 4307-4314. PMID: 30284448
- Identification of an eight-gene signature for survival prediction for patients with hepatocellular carcinoma based on integrated bioinformatics analysis. | Qiao, GJ., et al. 2019. PeerJ. 7: e6548. PMID: 30918751
- FAM163A, a positive regulator of ERK signaling pathway, interacts with 14-3-3β and promotes cell proliferation in squamous cell lung carcinoma. | Liu, N., et al. 2019. Onco Targets Ther. 12: 6393-6406. PMID: 31496741
- The Role of Aberrant DNA Methylation in Misregulation of Gene Expression in Gonadotroph Nonfunctioning Pituitary Tumors. | Kober, P., et al. 2019. Cancers (Basel). 11: PMID: 31731486
- Identification of novel loci influencing refractive error in East Asian populations using an extreme phenotype design. | Han, X., et al. 2022. J Genet Genomics. 49: 54-62. PMID: 34520856
- BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma. | Chen, YL., et al. 2022. Cell Biosci. 12: 33. PMID: 35303940
- Comprehensive Analysis of RNA-Seq in Endometriosis Reveals Competing Endogenous RNA Network Composed of circRNA, lncRNA and mRNA. | Yin, M., et al. 2022. Front Genet. 13: 828238. PMID: 35391800
- Melanocytic bronchial carcinoid tumor. | Cebelin, MS. 1980. Cancer. 46: 1843-8. PMID: 6253045
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM163A Antibody (B-8) | sc-390936 | 200 µg/ml | $316.00 | |||
FAM163A Antibody (B-8): m-IgG Fc BP-HRP Bundle | sc-540872 | 200 µg Ab; 10 µg BP | $354.00 | |||
FAM163A Antibody (B-8): m-IgG1 BP-HRP Bundle | sc-542432 | 200 µg Ab; 20 µg BP | $354.00 | |||
FAM163A (B-8) Neutralizing Peptide | sc-390936 P | 100 µg/0.5 ml | $68.00 |