FAM123A Antibody (G-1): sc-374654
- FAM123A Antibody (G-1) is a mouse monoclonal IgG2a κ FAM123A antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 603-637 near the C-terminus of FAM123A of human origin
- FAM123A Antibody (G-1) is recommended for detection of FAM123A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-FAM123A Antibody (G-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of FAM123A (G-1): sc-374654.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for FAM123A Antibody (G-1) for WB applications. This reagent is now offered in a bundle with FAM123A Antibody (G-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
QUICK LINKS
FAM123A Antibody (G-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects FAM123A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FAM123A (G-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FAM123A protein, encoded by the family with sequence similarity 123A gene, consists of 671 amino acids and plays a significant role in cellular processes, including cell adhesion and migration, which are crucial for tissue development and repair. FAM123A (G-1) monoclonal antibody targets a protein involved in regulating the Wnt signaling pathway, a key pathway that influences cell proliferation and differentiation, making FAM123A significant in both normal physiological processes and cancer biology. The gene encoding FAM123A is located on chromosome 13, a region that harbors several critical tumor suppressor genes, including BRCA2 and RB1, which are implicated in breast cancer and retinoblastoma, respectively. Understanding FAM123A function and interactions within these pathways can provide insights into potential roles in tumorigenesis and other diseases, highlighting anti-FAM123A antibody (G-1) significance in research applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
FAM123A Antibody (G-1) References:
- The DNA sequence and analysis of human chromosome 13. | Dunham, A., et al. 2004. Nature. 428: 522-8. PMID: 15057823
- Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome. | Deng, H., et al. 2006. Acta Neurol Scand. 114: 400-2. PMID: 17083340
- Non-disjunction of chromosome 13. | Bugge, M., et al. 2007. Hum Mol Genet. 16: 2004-10. PMID: 17584770
- Variable expressivity in Patau syndrome is not all related to trisomy 13 mosaicism. | Hsu, HF. and Hou, JW. 2007. Am J Med Genet A. 143A: 1739-48. PMID: 17603803
- The origin of trisomy 13. | Hall, HE., et al. 2007. Am J Med Genet A. 143A: 2242-8. PMID: 17853475
- Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. | Hassler, M., et al. 2007. Mol Cell. 28: 371-85. PMID: 17996702
- BRCA2: a universal recombinase regulator. | Thorslund, T. and West, SC. 2007. Oncogene. 26: 7720-30. PMID: 18066084
- A new gene for Tourette's syndrome: a window into causal mechanisms? | Grados, MA. and Walkup, JT. 2006. Trends Genet. 22: 291-3. PMID: 16678301
- RB and cell cycle progression. | Giacinti, C. and Giordano, A. 2006. Oncogene. 25: 5220-7. PMID: 16936740
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FAM123A Antibody (G-1) | sc-374654 | 200 µg/ml | $316.00 | |||
FAM123A Antibody (G-1): m-IgGκ BP-HRP Bundle | sc-522804 | 200 µg Ab, 40 µg BP | $354.00 | |||
FAM123A Antibody (G-1) AC | sc-374654 AC | 500 µg/ml, 25% agarose | $416.00 | |||
FAM123A Antibody (G-1) HRP | sc-374654 HRP | 200 µg/ml | $316.00 | |||
FAM123A Antibody (G-1) FITC | sc-374654 FITC | 200 µg/ml | $330.00 | |||
FAM123A Antibody (G-1) PE | sc-374654 PE | 200 µg/ml | $343.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 488 | sc-374654 AF488 | 200 µg/ml | $357.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 546 | sc-374654 AF546 | 200 µg/ml | $357.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 594 | sc-374654 AF594 | 200 µg/ml | $357.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 647 | sc-374654 AF647 | 200 µg/ml | $357.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 680 | sc-374654 AF680 | 200 µg/ml | $357.00 | |||
FAM123A Antibody (G-1) Alexa Fluor® 790 | sc-374654 AF790 | 200 µg/ml | $357.00 | |||
FAM123A (G-1) Neutralizing Peptide | sc-374654 P | 100 µg/0.5 ml | $68.00 |