FADD Antibody (F-12): sc-166516
- FADD Antibody (F-12) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 187-205 at the C-terminus of FADD of mouse origin
- recommended for detection of FADD of mouse and rat origin by WB, IP, IF and ELISA
- See FADD (G-4): sc-271748 for FADD antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FADD Antibody (F-12) for WB applications. These reagents are now offered in bundles with FADD Antibody (F-12) (see ordering information below).
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FADD Antibody (F-12) is a mouse monoclonal IgG1 kappa light chain antibody engineered to recognize the Fas-Associated Death Domain (FADD), also known as GIG3, or MORT1. FADD monoclonal antibody (F-12) targets an epitope located between amino acids 187-205 at the C-terminus of the mouse FADD protein, ensuring precise specificity and high affinity. FADD plays a critical role as an adaptor molecule in the apoptotic signaling pathways initiated by death receptors such as FAS and TNF receptors, facilitating the recruitment and activation of downstream caspases that execute programmed cell death. This function is essential for maintaining cellular homeostasis, regulating immune responses, and preventing uncontrolled cell proliferation, which is vital in cancer research and the study of various autoimmune diseases. FADD (F-12) antibody is validated for the detection of FADD in both mouse and rat species and is compatible with multiple applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). By enabling detailed investigation of FADD′s interactions and regulatory mechanisms, anti-FADD antibody (F-12) serves as an indispensable tool for researchers aiming to elucidate the complexities of apoptosis and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FADD Antibody (F-12) | sc-166516 | 200 µg/ml | $322.00 | |||
FADD Antibody (F-12): m-IgG Fc BP-HRP Bundle | sc-537500 | 200 µg Ab; 10 µg BP | $361.00 | |||
FADD Antibody (F-12): m-IgGκ BP-HRP Bundle | sc-534782 | 200 µg Ab; 40 µg BP | $361.00 | |||
FADD Antibody (F-12): m-IgG1 BP-HRP Bundle | sc-545204 | 200 µg Ab; 20 µg BP | $361.00 | |||
FADD (F-12) Neutralizing Peptide | sc-166516 P | 100 µg/0.5 ml | $69.00 |