Extracellular solute-binding protein Antibody (B-5): sc-398158
- Extracellular solute-binding protein Antibody (B-5) is a mouse monoclonal IgG2a κ Extracellular solute-binding protein antibody provided at 200 µg/ml
- raised against amino acids 1-288 representing full length Extracellular solute-binding protein of Streptococcus equi subsp. equi 4047 origin
- Extracellular solute-binding protein Antibody (B-5) is recommended for detection of Extracellular solute-binding protein of S. equi origin by WB, IP, IF and ELISA
- Anti-Extracellular solute-binding protein Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Extracellular solute-binding protein Antibody (B-5) for WB applications. These reagents are now offered in bundles with Extracellular solute-binding protein Antibody (B-5) (see ordering information below).
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Extracellular solute-binding protein Antibody (B-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Extracellular solute-binding protein of S. equi origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Extracellular solute-binding protein antibody (B-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Extracellular solute-binding protein plays a crucial role in transporting essential solutes across bacterial cell membranes, vital for survival and pathogenicity of Streptococcus equi. Through facilitating nutrient and small molecule uptake, Extracellular solute-binding protein helps bacteria adapt to host environments and evade immune responses, contributing to S. equi virulence. Understanding Extracellular solute-binding protein function is important for developing targeted therapies and vaccines against strangles, a highly contagious disease causing severe respiratory symptoms in equines. Strangles infection primarily spreads through inhalation or direct contact with infected secretions, making Extracellular solute-binding protein research essential for controlling outbreaks and improving animal health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Extracellular solute-binding protein Antibody (B-5) References:
- Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. | Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
- Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi. | Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
- Association of Streptococcus equi with equine monocytes. | Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
- Streptococcus equi: a pathogen restricted to one host. | Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
- Streptococcus equi subspecies equi infection (strangles) in horses. | Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
- Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component. | Flock, M., et al. 2012. Infect Immun. 80: 2914-9. PMID: 22615244
- Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model. | Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
- Detection of Streptococcus equi subspecies equi using a triplex qPCR assay. | Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Extracellular solute-binding protein Antibody (B-5) | sc-398158 | 200 µg/ml | $322.00 | |||
Extracellular solute-binding protein Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-530707 | 200 µg Ab; 10 µg BP | $361.00 | |||
Extracellular solute-binding protein Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-524235 | 200 µg Ab, 40 µg BP | $361.00 | |||
Extracellular solute-binding protein Antibody (B-5): m-IgG2a BP-HRP Bundle | sc-547566 | 200 µg Ab; 10 µg BP | $361.00 | |||
Extracellular solute-binding protein Antibody (B-5) AC | sc-398158 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Extracellular solute-binding protein Antibody (B-5) HRP | sc-398158 HRP | 200 µg/ml | $322.00 | |||
Extracellular solute-binding protein Antibody (B-5) FITC | sc-398158 FITC | 200 µg/ml | $336.00 | |||
Extracellular solute-binding protein Antibody (B-5) PE | sc-398158 PE | 200 µg/ml | $349.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 488 | sc-398158 AF488 | 200 µg/ml | $364.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 546 | sc-398158 AF546 | 200 µg/ml | $364.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 594 | sc-398158 AF594 | 200 µg/ml | $364.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 647 | sc-398158 AF647 | 200 µg/ml | $364.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 680 | sc-398158 AF680 | 200 µg/ml | $364.00 | |||
Extracellular solute-binding protein Antibody (B-5) Alexa Fluor® 790 | sc-398158 AF790 | 200 µg/ml | $364.00 |