Exportin 7 Antibody (A-11): sc-390025
- Exportin 7 Antibody (A-11) is a mouse monoclonal IgG1 κ Exportin 7 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 520-594 mapping within an internal region of Exportin 7 of human origin
- Exportin 7 Antibody (A-11) is recommended for detection of Exportin 7 of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- Anti-Exportin 7 Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Exportin 7 Antibody (A-11) for WB and IHC(P) applications. These reagents are now offered in bundles with Exportin 7 Antibody (A-11) (see ordering information below).
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Exportin 7 Antibody (A-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Exportin 7 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-Exportin 7 antibody (A-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Exportin 7, also known as RanBP16 or XPO7, is a 1,087 amino acid protein primarily expressed in the testis, thyroid, and bone marrow, with additional expression in the lung, liver, and small intestine. Exportin 7 plays a crucial role in the transport of proteins and large RNAs through the nuclear pore complex, facilitating translocation between the nucleus and cytoplasm. Localization of Exportin 7 in both the cytoplasm and nucleus ensures efficient cargo binding and transport in response to the nucleocytoplasmic RanGTP gradient. Exportin 7 interacts with proteins containing nuclear localization signals, which are essential for recognition and transport. Beyond transport functions, Exportin 7 is implicated in erythroid differentiation and may interact with cancer-associated proteins, suggesting a potential role in tumorigenesis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Exportin 7 Antibody (A-11) References:
- Identification of two novel RanGTP-binding proteins belonging to the importin beta superfamily. | Kutay, U., et al. 2000. J Biol Chem. 275: 40163-8. PMID: 11024021
- Identification of a novel putative Ran-binding protein and its close homologue. | Koch, P., et al. 2000. Biochem Biophys Res Commun. 278: 241-9. PMID: 11071879
- Exportin 7 defines a novel general nuclear export pathway. | Mingot, JM., et al. 2004. EMBO J. 23: 3227-36. PMID: 15282546
- STRADalpha regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. | Dorfman, J. and Macara, IG. 2008. Mol Biol Cell. 19: 1614-26. PMID: 18256292
- Evolutionary and transcriptional analysis of karyopherin beta superfamily proteins. | Quan, Y., et al. 2008. Mol Cell Proteomics. 7: 1254-69. PMID: 18353765
- High-resolution array CGH clarifies events occurring on 8p in carcinogenesis. | Cooke, SL., et al. 2008. BMC Cancer. 8: 288. PMID: 18840272
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Exportin 7 Antibody (A-11) | sc-390025 | 200 µg/ml | $316.00 | |||
Exportin 7 Antibody (A-11): m-IgG Fc BP-HRP Bundle | sc-530043 | 200 µg Ab; 10 µg BP | $354.00 | |||
Exportin 7 Antibody (A-11): m-IgGκ BP-HRP Bundle | sc-523371 | 200 µg Ab, 40 µg BP | $354.00 | |||
Exportin 7 Antibody (A-11): m-IgG1 BP-HRP Bundle | sc-543836 | 200 µg Ab; 20 µg BP | $354.00 | |||
Exportin 7 Antibody (A-11) AC | sc-390025 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Exportin 7 Antibody (A-11) HRP | sc-390025 HRP | 200 µg/ml | $316.00 | |||
Exportin 7 Antibody (A-11) FITC | sc-390025 FITC | 200 µg/ml | $330.00 | |||
Exportin 7 Antibody (A-11) PE | sc-390025 PE | 200 µg/ml | $343.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 488 | sc-390025 AF488 | 200 µg/ml | $357.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 546 | sc-390025 AF546 | 200 µg/ml | $357.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 594 | sc-390025 AF594 | 200 µg/ml | $357.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 647 | sc-390025 AF647 | 200 µg/ml | $357.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 680 | sc-390025 AF680 | 200 µg/ml | $357.00 | |||
Exportin 7 Antibody (A-11) Alexa Fluor® 790 | sc-390025 AF790 | 200 µg/ml | $357.00 |