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EURL Antibody (G-4): sc-390816

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Datasheets
  • EURL Antibody (G-4) is a mouse monoclonal IgG1 κ EURL antibody provided at 200 µg/ml
  • raised against amino acids 1-297 representing full length EURL of human origin
  • EURL Antibody (G-4) is recommended for detection of EURL of human origin by WB, IP, IF and ELISA
  • Anti-EURL Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EURL Antibody (G-4) for WB applications. These reagents are now offered in bundles with EURL Antibody (G-4) (see ordering information below).
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    EURL Antibody (G-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects EURL protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EURL (G-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. EURL protein, also known as C21orf91 or YG81, is a 297 amino acid protein characterized by a putative carboxy-terminal coiled-coil domain, which is crucial for protein-protein interactions and structural stability. EURL is predominantly expressed in the embryonic dorsal retina and anterior epithelial cells of the lens during later embryonic stages, suggesting a significant role in cell determination and differentiation processes. The gene encoding EURL is located on the long arm of chromosome 21, a region associated with various genetic disorders, including Alzheimer′s Disease, amyotrophic lateral sclerosis, and notably, Down Syndrome (trisomy 21). Understanding EURL function is vital, as this research may provide insights into the mechanisms underlying these conditions and contribute to the development of targeted therapies.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    EURL Antibody (G-4) References:

    1. Isolation of a novel cDNA enriched in the undifferentiated chick retina and lens.  |  Godbout, R., et al. 2003. Dev Dyn. 227: 409-15. PMID: 12815627
    2. Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis.  |  Yancey, SB., et al. 1992. Development. 114: 203-12. PMID: 1315676
    3. Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.  |  Levine, S., et al. 2009. Exp Mol Pathol. 86: 18-22. PMID: 19041304
    4. Lens epithelial cell mRNA, II. Expression of a mRNA encoding a lipid-binding protein in rat lens epithelial cells.  |  Wen, Y., et al. 1995. Gene. 158: 269-74. PMID: 7607553
    5. Chicken Eyes absent 2 gene: isolation and expression pattern during development.  |  Mishima, N. and Tomarev, S. 1998. Int J Dev Biol. 42: 1109-15. PMID: 9879708

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    EURL Antibody (G-4)

    sc-390816
    200 µg/ml
    $322.00

    EURL Antibody (G-4): m-IgG Fc BP-HRP Bundle

    sc-530273
    200 µg Ab; 10 µg BP
    $361.00

    EURL Antibody (G-4): m-IgGκ BP-HRP Bundle

    sc-523695
    200 µg Ab, 40 µg BP
    $361.00

    EURL Antibody (G-4): m-IgG1 BP-HRP Bundle

    sc-543968
    200 µg Ab; 20 µg BP
    $361.00

    EURL Antibody (G-4) AC

    sc-390816 AC
    500 µg/ml, 25% agarose
    $424.00

    EURL Antibody (G-4) HRP

    sc-390816 HRP
    200 µg/ml
    $322.00

    EURL Antibody (G-4) FITC

    sc-390816 FITC
    200 µg/ml
    $336.00

    EURL Antibody (G-4) PE

    sc-390816 PE
    200 µg/ml
    $349.00

    EURL Antibody (G-4) Alexa Fluor® 488

    sc-390816 AF488
    200 µg/ml
    $364.00

    EURL Antibody (G-4) Alexa Fluor® 546

    sc-390816 AF546
    200 µg/ml
    $364.00

    EURL Antibody (G-4) Alexa Fluor® 594

    sc-390816 AF594
    200 µg/ml
    $364.00

    EURL Antibody (G-4) Alexa Fluor® 647

    sc-390816 AF647
    200 µg/ml
    $364.00

    EURL Antibody (G-4) Alexa Fluor® 680

    sc-390816 AF680
    200 µg/ml
    $364.00

    EURL Antibody (G-4) Alexa Fluor® 790

    sc-390816 AF790
    200 µg/ml
    $364.00

    What blocking solution should I use with EURL (G-4): sc-390816 monoclonal antibody for Western blot?

    Asked by: Randy McDonald
    Thank you for your question. We recommend blocking with Blotto (either TBS Blotto A: sc-2333 or TBS Blotto B: sc-2335). Our Western blot protocol can be found here: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of EURLProduced positive Western blot data of EURL expression in A-431 nuclear extract and Y79 whole cell lysate . -SCBT QC
    Date published: 2014-08-24
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    EURL Antibody (G-4) is rated 5.0 out of 5 by 1.
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