Ets-2 Antibody (F-4): sc-373754
- Ets-2 Antibody (F-4) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 441-469 at the C-terminus of Ets-2 of human origin
- recommended for detection of Ets-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and bovine
- TransCruz reagent for ChIP application (sc-373754 X, 200 µg/0.1 ml)
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ets-2 Antibody (F-4) for WB applications. These reagents are now offered in bundles with Ets-2 Antibody (F-4) (see ordering information below).
Ets-2 Antibody (F-4) is a mouse monoclonal IgG2b kappa light chain antibody designed to recognize the Ets-2 protein. Anti-Ets-2 antibody (F-4) targets an epitope mapping to amino acids 441-469 at the C-terminus of human Ets-2, enabling effective detection in mouse, rat, human, canine, and bovine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ets-2 is a vital transcription factor within the ETS family, playing a crucial role in regulating genes involved in cellular processes like proliferation, differentiation, apoptosis, and angiogenesis. Structurally, Ets-2 contains a conserved ETS DNA-binding domain that facilitates interaction with specific DNA sequences, allowing control of gene expression and maintenance of cellular homeostasis. Post-translational modifications, particularly phosphorylation, are essential for modulating Ets-2′s transcriptional activity and ability to interact with other regulatory proteins, thereby fine-tuning function in various biological contexts. Nuclear localization of Ets-2 is critical for gene regulation, ensuring effective control of target gene expression within the cell nucleus. Dysregulation of Ets-2 has been associated with numerous cancers and developmental disorders, highlighting significance in both normal physiology and disease pathology. Ets-2 (F-4) antibody is available in non-conjugated form as well as multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatile options for diverse experimental needs. By utilizing Ets-2 (F-4) monoclonal antibody, researchers can thoroughly investigate structural and functional roles of Ets-2 in gene regulation, advancing understanding of involvement in processes such as cancer progression, developmental biology, and molecular signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ets-2 Antibody (F-4) | sc-373754 | 200 µg/ml | $322.00 | |||
Ets-2 Antibody (F-4): m-IgGκ BP-HRP Bundle | sc-535306 | 200 µg Ab; 40 µg BP | $361.00 | |||
Ets-2 Antibody (F-4): m-IgG2b BP-HRP Bundle | sc-549388 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ets-2 (F-4) Neutralizing Peptide | sc-373754 P | 100 µg/0.5 ml | $69.00 | |||
Ets-2 Antibody (F-4) X | sc-373754 X | 200 µg/0.1 ml | $322.00 |