Epithelial sialomucin Antibody (140 C1): sc-52329
- Epithelial sialomucin Antibody (140 C1) is a mouse monoclonal IgG1 Epithelial sialomucin antibody, cited in 1 publications, provided at 500 µl ascites
- raised against isolated primary breast carcinoma cells of human origin
- recommended for detection of Epithelial sialomucin, a mucus glycoprotein also known as MAM-6 (milkfat globule membrane antigen 6). Epithelial sialomucin (140 C1) is an excellent marker for various epithelial carcinomas. of human origin by IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Epithelial sialomucin Antibody (140 C1). This work is in progress.
Epithelial sialomucin Antibody (140 C1) is a mouse monoclonal IgG1 antibody that detects Epithelial sialomucin of human origin by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Epithelial sialomucin antibody (140 C1) is available as a non-conjugated format. Epithelial sialomucin, also known as ESM or MAM-6 (milk fat globule membrane antigen 6), is a crucial tumor marker that plays a significant role in oncology, showing normal levels in non-cancerous tissues but elevated levels in various epithelial carcinomas. This glycoprotein is primarily located in the glycocalyx of normal glandular epithelial cells and is also present in malignant glands of endocervical and endometrial tissues. Epithelial sialomucin serves as a marker for mammary and other skin appendage/epithelial tumors, aiding in cancer diagnosis and monitoring. Epithelial sialomucin also participates in cell signaling and adhesion processes, which are vital for maintaining tissue integrity and function. Anti-Epithelial sialomucin antibody (140 C1) enables valuable insights into cancer biology research and therapeutic target development.
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Epithelial sialomucin Antibody (140 C1) References:
- Immunohistochemical localization of MAM-3 and MAM-6 antigens in adenoid cystic carcinoma. | Yamada, K., et al. 1991. J Oral Pathol Med. 20: 57-63. PMID: 1849991
- Immunohistochemical distribution of MAM-3 and MAM-6 antigens in developing salivary glands of the human fetus. | Lee, SK., et al. 1991. Histochem J. 23: 355-60. PMID: 1917564
- Immunohistochemical study of a monoclonal antibody 115D8 against human milk-fat globule membrane (MAM-6) in some histological types of breast cancer. | Shibuya, C., et al. 1990. Nihon Geka Hokan. 59: 295-301. PMID: 2130793
- Immunohistochemical expression of MAM-3 and MAM-6 antigens in salivary gland tumours. | Yamada, K., et al. 1989. Virchows Arch A Pathol Anat Histopathol. 415: 509-21. PMID: 2508309
- Biosynthesis of MAM-6, an epithelial sialomucin. Evidence for involvement of a rare proteolytic cleavage step in the endoplasmic reticulum. | Hilkens, J. and Buijs, F. 1988. J Biol Chem. 263: 4215-22. PMID: 3346246
- Immunohistochemical localization of the epithelial marker MAM-6 in invasive malignancies and highly dysplastic adenomas of the large intestine. | Zotter, S., et al. 1987. Lab Invest. 57: 193-9. PMID: 3613527
- MAM-6 antigen, a new serum marker for breast cancer monitoring. | Hilkens, J., et al. 1986. Cancer Res. 46: 2582-7. PMID: 3697998
- Expression of MAM-3 and MAM-6 antigens in endometrial and endocervical adenocarcinomas. | Tsubura, A., et al. 1985. Virchows Arch A Pathol Anat Histopathol. 407: 59-67. PMID: 3925626
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Epithelial sialomucin Antibody (140 C1) | sc-52329 | 500 µl ascites | $316.00 |