ephrin-A3 Antibody (G-11): sc-398331
- ephrin-A3 Antibody (G-11) is a mouse monoclonal mouse IgG1 κ κ provided at 200 µg/ml
- raised against amino acids 149-238 mapping at the C-terminus of ephrin-A3 of human origin
- recommended for detection of ephrin-A3 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ephrin-A3 Antibody (G-11) for WB applications. These reagents are now offered in bundles with ephrin-A3 Antibody (G-11) (see ordering information below).
ephrin-A3 Antibody (G-11) is a mouse monoclonal IgG1 antibody that detects ephrin-A3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Ephrin-A3 plays a crucial role in cell signaling and communication, particularly in the development of the nervous system, where ephrin-A3 is involved in the regulation of neuronal growth and guidance. Ephrin-A3 is primarily located on the cell surface, where ephrin-A3 interacts with Eph receptors, facilitating bidirectional signaling that influences cell positioning and movement during embryonic development. Ephrin-A3′s location is key for processes such as axon guidance and synaptic plasticity, which are vital for proper neural network formation and function. Additionally, ephrin-A3 interacts with various Eph receptors, including EphA3 and EphA5, highlighting ephrin-A3′s role in mediating complex signaling pathways essential for cellular communication and tissue organization. Anti-ephrin-A3 antibody (G-11) is an invaluable tool for researchers studying these critical biological processes and their implications in neurodevelopmental disorders and other diseases.
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ephrin-A3 Antibody (G-11) References:
- Identification and characterization of splice variants of ephrin-A3 and ephrin-A5. | Lai, KO., et al. 1999. FEBS Lett. 458: 265-9. PMID: 10481078
- Ephrin-A3 not only increases the density of hair follicles but also accelerates anagen development in neonatal mice. | Yamada, Y., et al. 2008. J Dermatol Sci. 52: 178-85. PMID: 18640011
- Heparan sulfate regulates ephrin-A3/EphA receptor signaling. | Irie, F., et al. 2008. Proc Natl Acad Sci U S A. 105: 12307-12. PMID: 18715996
- Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport. | Carmona, MA., et al. 2009. Proc Natl Acad Sci U S A. 106: 12524-9. PMID: 19592509
- Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. | Filosa, A., et al. 2009. Nat Neurosci. 12: 1285-92. PMID: 19734893
- Ephrin-A3 suppresses Wnt signaling to control retinal stem cell potency. | Fang, Y., et al. 2013. Stem Cells. 31: 349-59. PMID: 23165658
- Ephrin-A3 promotes and maintains slow muscle fiber identity during postnatal development and reinnervation. | Stark, DA., et al. 2015. J Cell Biol. 211: 1077-91. PMID: 26644518
- The role of miR-210, E2F3 and ephrin A3 in angiosarcoma cell proliferation. | Nakashima, S., et al. 2017. Eur J Dermatol. 27: 464-471. PMID: 28739548
- Normal muscle fiber type distribution is recapitulated in aged ephrin-A3-/- mice that previously lacked most slow myofibers. | Arpke, RW., et al. 2023. Am J Physiol Cell Physiol. 324: C718-C727. PMID: 36717102
- Transcriptional regulation of the mouse EphA4, Ephrin-B2 and Ephrin-A3 genes by the circadian clock machinery. | Ballester Roig, MN., et al. 2023. Chronobiol Int. 40: 983-1003. PMID: 37551686
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ephrin-A3 Antibody (G-11) | sc-398331 | 200 µg/ml | $322.00 | |||
ephrin-A3 Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-538421 | 200 µg Ab; 10 µg BP | $361.00 | |||
ephrin-A3 Antibody (G-11): m-IgGκ BP-HRP Bundle | sc-536033 | 200 µg Ab; 40 µg BP | $361.00 |