EphA1 Antibody (5D2A10): sc-65994

EphA1 Antibody (5D2A10) is a mouse monoclonal IgG1 antibody that detects EphA1 in human samples through applications such as western blotting (WB) and immunofluorescence (IF). EphA1 is a member of the Eph receptor subfamily, which represents the largest group of receptor protein tyrosine kinases identified to date, playing a crucial role in various biological processes, particularly in the central nervous system and during developmental stages. EphA1 protein is primarily located on the cell surface, where EphA1 interacts with ephrin-A4 and ephrin-A2 ligands, facilitating cell signaling pathways essential for cell positioning, migration, and communication. This spatial regulation is vital for proper neuronal development and function, as EphA1 influences the formation of synapses and the overall architecture of neural networks. EphA1′s involvement in these processes underscores its importance in both normal physiology and potential pathologies, such as neurodegenerative diseases and cancer, making anti-EphA1 antibody (5D2A10) an invaluable tool for researchers studying these critical areas.