Ep-CAM Antibody (9C4): sc-21792
- Ep-CAM Antibody (9C4) is a mouse monoclonal IgG2b κ, cited in 8 publications, provided at 200 µg/ml
- raised against DU4475 breast carcinoma cell line
- Ep-CAM Antibody (9C4) is recommended for detection of Ep-CAM of human origin by IF, IHC(P) and FCM
- Anti-Ep-CAM Antibody (9C4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Ep-CAM Antibody (9C4) for IHC(P) applications. This reagent is now offered in a bundle with Ep-CAM Antibody (9C4) (see ordering information below).
QUICK LINKS
SEE ALSO...
Ep-CAM Antibody (9C4) is a mouse monoclonal IgG2b kappa light chain antibody that detects Ep-CAM of human origin by immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-Ep-CAM antibody (9C4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. The epithelial cell adhesion molecule, also known as tumor-associated calcium signal transducer 1 and MK-1, plays a crucial role in cell-cell adhesion and is predominantly expressed in normal human epithelial tissues as well as in various carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that exists in two forms, with the major form being more prevalent; interestingly, the expression of these forms can be altered by the amino-glycosylation inhibitor tunicamycin. Notably, Ep-CAM is often overexpressed in a range of carcinomas, making Ep-CAM a significant target for both visualization and therapeutic strategies in human solid tumors. The protein features an extracellular domain that includes two epidermal growth factor-like repeats, which are essential for adhesive properties, thereby highlighting Ep-CAM′s importance in maintaining tissue architecture and integrity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ep-CAM Antibody (9C4) | sc-21792 | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (9C4): m-IgG Fc BP-HRP Bundle | sc-525507 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ep-CAM Antibody (9C4) AC | sc-21792 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Ep-CAM Antibody (9C4) HRP | sc-21792 HRP | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (9C4) FITC | sc-21792 FITC | 200 µg/ml | $336.00 | |||
Ep-CAM Antibody (9C4) PE | sc-21792 PE | 200 µg/ml | $349.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 488 | sc-21792 AF488 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 546 | sc-21792 AF546 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 594 | sc-21792 AF594 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 647 | sc-21792 AF647 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 680 | sc-21792 AF680 | 200 µg/ml | $364.00 | |||
Ep-CAM Antibody (9C4) Alexa Fluor® 790 | sc-21792 AF790 | 200 µg/ml | $364.00 |