Ep-CAM Activators
Ep-CAM Activators encompass a diverse set of chemicals that, either directly or more commonly, indirectly modulate the expression or function of the Ep-CAM protein. Ep-CAM, also known as epithelial cell adhesion molecule, plays crucial roles in cell-to-cell adhesion, proliferation, differentiation, and signaling, especially within epithelial tissues. Some molecules, such as retinoic acid or 17β-estradiol, influence Ep-CAM through nuclear receptor pathways and subsequent transcriptional regulation.
Furthermore, Ep-CAM's role as a marker for certain stem cell populations and its involvement in epithelial cancers also draw attention to the relevance of its chemical modulators. Genistein and PGE2, for example, showcase the complexities of Ep-CAM's regulation in the context of oncology. While the direct chemical interaction with Ep-CAM might not be the primary modus operandi for many of these molecules, their influence on cellular pathways that interplay with Ep-CAM's function and expression are noteworthy.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Can stimulate Ep-CAM expression in epithelial cells through metabolic pathways. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Stimulates Ep-CAM expression in certain epithelial cells via estrogen receptors. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 can modulate Ep-CAM expression in colorectal cancer cells. | ||||||
Lysophosphatidic Acid | 325465-93-8 | sc-201053 sc-201053A | 5 mg 25 mg | $98.00 $341.00 | 50 | |
Known to increase Ep-CAM expression in ovarian cancer cells. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Glucocorticoid that can elevate Ep-CAM levels in certain contexts. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Isoflavone known to enhance Ep-CAM expression in breast cancer cells. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates cAMP levels leading to potential elevation of Ep-CAM expression in specific cell types. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $306.00 $963.00 $7980.00 | 1 | |
May influence Ep-CAM through metabolic modulation, especially in energy-dependent cellular processes. | ||||||