Ep-CAM Antibody (323/A3): sc-73491
- Ep-CAM Antibody (323/A3) is a mouse monoclonal IgG1 κ, cited in 5 publications, provided at 200 µg/ml
- raised against MCF-7 human breast cancer cells of human origin
- recommended for detection of Ep-CAM of mouse, rat and human origin by WB, IP, IF and IHC(P); may cross-react with most epithelial cells and carcinomas
- See Ep-CAM (C-10): sc-25308 for Ep-CAM antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Ep-CAM Antibody (323/A3) for WB and IHC(P) applications. This reagent is now offered in a bundle with Ep-CAM Antibody (323/A3) (see ordering information below).
QUICK LINKS
SEE ALSO...
Ep-CAM Antibody (323/A3) is a mouse monoclonal IgG1 antibody that detects Ep-CAM in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Ep-CAM, also known as tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein predominantly expressed in normal human epithelial tissues and various carcinomas, making Ep-CAM a significant marker for cancer research. Ep-CAM consists of 314 amino acids and exists in two forms, with the major form being more prevalent; both forms are affected by the amino-glycosylation inhibitor tunicamycin, which reduces their expression. The extracellular domain of Ep-CAM features two epidermal growth factor-like repeats followed by a cysteine-poor region, which is crucial for adhesive properties, facilitating cell-cell interactions that are vital for maintaining tissue integrity. Given Ep-CAM′s overexpression in numerous carcinomas, anti-Ep-CAM antibody (323/A3) serves as a promising tool for both visualization and therapeutic intervention of solid tumors, highlighting Ep-CAM′s importance in cancer diagnostics and treatment strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ep-CAM Antibody (323/A3) | sc-73491 | 200 µg/ml | $322.00 | |||
Ep-CAM Antibody (323/A3): m-IgG Fc BP-HRP Bundle | sc-539488 | 200 µg Ab; 10 µg BP | $361.00 |