eotaxin-3 Antibody (4i22) is a mouse monoclonal IgG1 antibody that detects eotaxin-3 protein of human origin by enzyme-linked immunosorbent assay (ELISA). anti-eotaxin-3 antibody (4i22) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important chemokine. eotaxin-3 plays a crucial role in the immune response by mediating the migration of eosinophils and basophils, which are essential for combating parasitic infections and modulating allergic reactions. eotaxin-3 is produced primarily by various cell types, including epithelial cells and fibroblasts, and expression increases significantly in response to inflammatory stimuli. This localization and regulation ensure eosinophil recruitment to sites of inflammation, contributing to tissue repair and immune defense. The gene encoding eotaxin-3 is located on human chromosome 7q11.23, and unique ability to induce eosinophil migration at a concentration ten times lower than eotaxin-2 highlights potency and importance in the chemokine network. eotaxin-3 monoclonal antibody (4i22) enables researchers to gain deeper insights into the mechanisms of eosinophil recruitment and broader implications for allergic diseases and asthma.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eotaxin-3 Antibody (4i22) | sc-71055 | 100 µg/ml | $322.00 |