Date published: 2025-11-24

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Endophilin B2 Antibody (C-10): sc-271129

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Datasheets
  • Endophilin B2 Antibody (C-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against amino acids 81-140 mapping near the N-terminus of Endophilin B2 of human origin
  • recommended for detection of Endophilin B2 of human origin by WB, IP, IF, IHC(P) and ELISA
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Endophilin B2 Antibody (C-10) for WB and IHC(P) applications. These reagents are now offered in bundles with Endophilin B2 Antibody (C-10) (see ordering information below).

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    Endophilin B2 Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects Endophilin B2 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Endophilin B2 plays a crucial role in the regulation of synaptic vesicle trafficking and is essential for maintaining mitochondrial morphology and dynamics, which are vital for cellular energy production and signaling. Endophilin B2 is predominantly expressed in the brain, adult lung, ovary, and spinal cord, highlighting its importance in both neuronal function and overall cellular health. Notably, decreased levels of Endophilin B2 have been associated with Down Syndrome, suggesting that alterations in expression may contribute to brain dysgenesis and other neurological disorders. Anti-Endophilin B2 antibody (C-10) provides a valuable tool for researchers investigating the molecular mechanisms underlying these conditions, as well as for studying the broader implications of mitochondrial dynamics in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Endophilin B2 Antibody (C-10)

    sc-271129
    200 µg/ml
    $316.00

    Endophilin B2 Antibody (C-10): m-IgG Fc BP-HRP Bundle

    sc-540210
    200 µg Ab; 10 µg BP
    $354.00

    Endophilin B2 Antibody (C-10): m-IgG1 BP-HRP Bundle

    sc-541973
    200 µg Ab; 20 µg BP
    $354.00

    Can Endophilin B2 (C-10): sc-271129 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: AbPolly
    Thank you for your question. Yes, Endophilin B2 (C-10): sc-271129 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 4 out of 5 by from Strong bands seen in WB using UStrong bands seen in WB using U-87 MG and HeLa whole cell lysates. -SCBT QC
    Date published: 2015-02-03
    Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
    Date published: 2015-01-28
    Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human urinary bladder tissue. -SCBT QC
    Date published: 2015-01-25
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    Endophilin B2 Antibody (C-10) is rated 4.3 out of 5 by 3.
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