Endophilin B2 Antibody (A-10): sc-365608
- Endophilin B2 Antibody (A-10) is a mouse monoclonal IgG1 κ Endophilin B2 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 181-209 within an internal region of Endophilin B2 of human origin
- Endophilin B2 Antibody (A-10) is recommended for detection of all isoforms of Endophilin B2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-Endophilin B2 Antibody (A-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Endophilin B2 Antibody (A-10) for WB applications. These reagents are now offered in bundles with Endophilin B2 Antibody (A-10) (see ordering information below).
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Endophilin B2 Antibody (A-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Endophilin B2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Endophilin B2 antibody (A-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Endophilin B2 plays a crucial role in regulating synaptic vesicle trafficking, which is essential for neurotransmitter release and communication between neurons. Endophilin B2 is predominantly located in the brain, adult lung, ovary, and spinal cord, highlighting its importance in neuronal function and development. Notably, Endophilin B2 interacts with other key proteins involved in synaptic processes, such as Amphiphysin, Synaptojanin, and Dynamin, forming a complex that is vital for maintaining synaptic transmission integrity. Alterations in Endophilin B2 expression have been associated with neurological disorders, including Down Syndrome, where decreased levels may indicate underlying brain dysgenesis. Endophilin B2 (A-10) monoclonal antibody′s ability to effectively detect across multiple species and applications makes this product an invaluable tool for researchers studying synaptic function and related pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Endophilin B2 Antibody (A-10) References:
- SH3GLB, a new endophilin-related protein family featuring an SH3 domain. | Pierrat, B., et al. 2001. Genomics. 71: 222-34. PMID: 11161816
- Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. | Modregger, J., et al. 2003. J Biol Chem. 278: 4160-7. PMID: 12456676
- Aberrant protein expression in cerebral cortex of fetus with Down syndrome. | Engidawork, E., et al. 2003. Neuroscience. 122: 145-54. PMID: 14596856
- Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production. | Wang, MQ., et al. 2003. J Biol. 3: 4. PMID: 14659004
- Endophilin B1 is required for the maintenance of mitochondrial morphology. | Karbowski, M., et al. 2004. J Cell Biol. 166: 1027-39. PMID: 15452144
- Direct interaction between metastasis-associated protein 1 and endophilin 3. | Aramaki, Y., et al. 2005. FEBS Lett. 579: 3731-6. PMID: 15978591
- Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis. | Takahashi, Y., et al. 2005. Mol Cell Biol. 25: 9369-82. PMID: 16227588
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Endophilin B2 Antibody (A-10) | sc-365608 | 200 µg/ml | $316.00 | |||
Endophilin B2 Antibody (A-10): m-IgG Fc BP-HRP Bundle | sc-529407 | 200 µg Ab; 10 µg BP | $354.00 | |||
Endophilin B2 Antibody (A-10): m-IgGκ BP-HRP Bundle | sc-522291 | 200 µg Ab, 40 µg BP | $354.00 | |||
Endophilin B2 Antibody (A-10) AC | sc-365608 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Endophilin B2 Antibody (A-10) HRP | sc-365608 HRP | 200 µg/ml | $316.00 | |||
Endophilin B2 Antibody (A-10) FITC | sc-365608 FITC | 200 µg/ml | $330.00 | |||
Endophilin B2 Antibody (A-10) PE | sc-365608 PE | 200 µg/ml | $343.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 488 | sc-365608 AF488 | 200 µg/ml | $357.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 546 | sc-365608 AF546 | 200 µg/ml | $357.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 594 | sc-365608 AF594 | 200 µg/ml | $357.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 647 | sc-365608 AF647 | 200 µg/ml | $357.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 680 | sc-365608 AF680 | 200 µg/ml | $357.00 | |||
Endophilin B2 Antibody (A-10) Alexa Fluor® 790 | sc-365608 AF790 | 200 µg/ml | $357.00 | |||
Endophilin B2 (A-10) Neutralizing Peptide | sc-365608 P | 100 µg/0.5 ml | $68.00 |