ENDOD1 Antibody (G-1): sc-515153
- ENDOD1 Antibody (G-1) is a mouse monoclonal IgG1 κ ENDOD1 antibody provided at 200 µg/ml
- raised against amino acids 29-212 mapping near the N-terminus of ENDOD1 of human origin
- ENDOD1 Antibody (G-1) is recommended for detection of ENDOD1 of human origin by WB, IP, IF and ELISA
- Anti-ENDOD1 Antibody (G-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ENDOD1 Antibody (G-1) for WB applications. These reagents are now offered in bundles with ENDOD1 Antibody (G-1) (see ordering information below).
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SEE ALSO...
ENDOD1 Antibody (G-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects ENDOD1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-ENDOD1 antibody (G-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ENDOD1, or endonuclease domain-containing 1 protein, is a 500 amino acid secreted protein that plays a crucial role in cellular processes by functioning as a deoxyribonuclease and ribonuclease, which are essential for the degradation of nucleic acids. This activity is particularly important for maintaining cellular homeostasis and regulating gene expression, as ENDOD1 helps eliminate damaged or excess RNA and DNA, thereby preventing potential genomic instability. The gene encoding ENDOD1 is located on human chromosome 11, a region known for its association with various genetic disorders, including ataxia-telangiectasia, which is linked to mutations in the Atm gene that is also found on this chromosome. ENDOD1′s ability to interact with other proteins involved in nucleic acid metabolism further underscores its significance in cellular function and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ENDOD1 Antibody (G-1) References:
- Hereditary angioedema. Long-term follow-up of 88 patients. Experience of the Argentine Allergy and Immunology Institute. | Fabiani, JE., et al. 2000. Allergol Immunopathol (Madr). 28: 267-71. PMID: 11270087
- Smith-Lemli-Opitz syndrome and the DHCR7 gene. | Jira, PE., et al. 2003. Ann Hum Genet. 67: 269-80. PMID: 12914579
- The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann-Pick disease. | Schuchman, EH. 2007. J Inherit Metab Dis. 30: 654-63. PMID: 17632693
- Jervell and Lange-Nielsen syndrome in Norwegian children: aspects around cochlear implantation, hearing, and balance. | Siem, G., et al. 2008. Ear Hear. 29: 261-9. PMID: 18595190
- Chromosomal microarray mapping suggests a role for BSX and Neurogranin in neurocognitive and behavioral defects in the 11q terminal deletion disorder (Jacobsen syndrome). | Coldren, CD., et al. 2009. Neurogenetics. 10: 89-95. PMID: 18855024
- An intronic mutation leading to incomplete skipping of exon-2 in KCNQ1 rescues hearing in Jervell and Lange-Nielsen syndrome. | Bhuiyan, ZA., et al. 2008. Prog Biophys Mol Biol. 98: 319-27. PMID: 19027783
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ENDOD1 Antibody (G-1) | sc-515153 | 200 µg/ml | $322.00 | |||
ENDOD1 Antibody (G-1): m-IgGκ BP-HRP Bundle | sc-524957 | 200 µg Ab, 40 µg BP | $361.00 | |||
ENDOD1 Antibody (G-1): m-IgG1 BP-HRP Bundle | sc-533642 | 200 µg Ab; 20 µg BP | $361.00 | |||
ENDOD1 Antibody (G-1) AC | sc-515153 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ENDOD1 Antibody (G-1) HRP | sc-515153 HRP | 200 µg/ml | $322.00 | |||
ENDOD1 Antibody (G-1) FITC | sc-515153 FITC | 200 µg/ml | $336.00 | |||
ENDOD1 Antibody (G-1) PE | sc-515153 PE | 200 µg/ml | $349.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 488 | sc-515153 AF488 | 200 µg/ml | $364.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 546 | sc-515153 AF546 | 200 µg/ml | $364.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 594 | sc-515153 AF594 | 200 µg/ml | $364.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 647 | sc-515153 AF647 | 200 µg/ml | $364.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 680 | sc-515153 AF680 | 200 µg/ml | $364.00 | |||
ENDOD1 Antibody (G-1) Alexa Fluor® 790 | sc-515153 AF790 | 200 µg/ml | $364.00 |