
EMMPRIN Antibody (UM-8D6) is a mouse monoclonal IgG1 antibody that detects EMMPRIN in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). EMMPRIN, also known as basigin or CD147, plays a crucial role in the regulation of matrix remodeling at the epidermal-dermal interface, where EMMPRIN stimulates fibroblasts to produce key enzymes such as interstitial collagenase, gelatinase A, and stromelysin-1, as well as various metalloproteinases (MMPs). These enzymes are particularly significant during tissue degradation and wound healing, as MMPs facilitate the breakdown of extracellular matrix components, which is essential for normal physiological processes. Dysregulation of EMMPRIN and associated metalloproteinases has been implicated in cancer invasion and metastasis, making anti-EMMPRIN antibody (UM-8D6) an invaluable tool for researchers investigating EMMPRIN′s complex roles in both normal and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EMMPRIN/CD147 Antibody (UM-8D6) | sc-80545 | 200 µg/ml | $322.00 | |||
EMMPRIN/CD147 Antibody (UM-8D6): m-IgGκ BP-HRP Bundle | sc-521156 | 200 µg Ab, 40 µg BP | $361.00 |