EMID1 Antibody (G-12): sc-390288
- EMID1 Antibody (G-12) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 383-417 within an internal region of EMID1 of human origin
- Anti-EMID1 Antibody (G-12) is recommended for detection of EMID1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-EMID1 Antibody (G-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EMID1 Antibody (G-12) for WB applications. These reagents are now offered in bundles with EMID1 Antibody (G-12) (see ordering information below).
QUICK LINKS
EMID1 Antibody (G-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects EMID1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EMID1 antibody (G-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. EMID1, or EMI domain containing 1, is a 441 amino acid secreted protein characterized by the presence of one collagen-like domain and one EMI domain, which is notable for containing seven conserved cysteines that may facilitate dimerization. This structural feature is crucial as it suggests a potential role in protein-protein interactions, which can influence various cellular processes, including signaling pathways and extracellular matrix organization. The EMID1 gene, located on human chromosome 22q12.2, spans 54 kb and consists of 15 exons, giving rise to three alternatively spliced isoforms. The conservation of EMID1 across species such as chimpanzee, dog, cow, mouse, rat, chicken, and zebrafish highlights its evolutionary significance. Chromosome 22, being the second smallest human chromosome, harbors over 500 genes and is associated with several genetic disorders, including Phelan-McDermid syndrome and neurofibromatosis type 2, making EMID1 and its interactions particularly relevant in understanding these conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
EMID1 Antibody (G-12) References:
- Chromosome 22 workshop report. | Schwab, SG. and Wildenauer, DB. 1999. Am J Med Genet. 88: 276-8. PMID: 10374745
- Disease genes and chromosomes: disease maps of the human genome. Chromosome 22. | Gilbert, F. 1998. Genet Test. 2: 89-97. PMID: 10464604
- The DNA sequence of human chromosome 22. | Dunham, I., et al. 1999. Nature. 402: 489-95. PMID: 10591208
- Developmental expression and biochemical characterization of Emu family members. | Leimeister, C., et al. 2002. Dev Biol. 249: 204-18. PMID: 12221002
- Analyses of the associations between the genes of 22q11 deletion syndrome and schizophrenia. | Arinami, T. 2006. J Hum Genet. 51: 1037-1045. PMID: 16969581
- Deletion 22q11: spectrum of associated disorders. | Hay, BN. 2007. Semin Pediatr Neurol. 14: 136-9. PMID: 17980310
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EMID1 Antibody (G-12) | sc-390288 | 200 µg/ml | $316.00 | |||
EMID1 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-530119 | 200 µg Ab; 10 µg BP | $354.00 | |||
EMID1 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-523478 | 200 µg Ab, 40 µg BP | $354.00 | |||
EMID1 Antibody (G-12): m-IgG1 BP-HRP Bundle | sc-543878 | 200 µg Ab; 20 µg BP | $354.00 | |||
EMID1 Antibody (G-12) AC | sc-390288 AC | 500 µg/ml, 25% agarose | $416.00 | |||
EMID1 Antibody (G-12) HRP | sc-390288 HRP | 200 µg/ml | $316.00 | |||
EMID1 Antibody (G-12) FITC | sc-390288 FITC | 200 µg/ml | $330.00 | |||
EMID1 Antibody (G-12) PE | sc-390288 PE | 200 µg/ml | $343.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 488 | sc-390288 AF488 | 200 µg/ml | $357.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 546 | sc-390288 AF546 | 200 µg/ml | $357.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 594 | sc-390288 AF594 | 200 µg/ml | $357.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 647 | sc-390288 AF647 | 200 µg/ml | $357.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 680 | sc-390288 AF680 | 200 µg/ml | $357.00 | |||
EMID1 Antibody (G-12) Alexa Fluor® 790 | sc-390288 AF790 | 200 µg/ml | $357.00 | |||
EMID1 (G-12) Neutralizing Peptide | sc-390288 P | 100 µg/0.5 ml | $68.00 |