EMC7 Antibody (F-3): sc-514440
- EMC7 Antibody (F-3) is a mouse monoclonal IgG1 κ EMC7 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 66-225 mapping within an N-terminal extracellular domain of EMC7 of human origin
- EMC7 Antibody (F-3) is recommended for detection of EMC7 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-EMC7 Antibody (F-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EMC7 Antibody (F-3) for WB applications. These reagents are now offered in bundles with EMC7 Antibody (F-3) (see ordering information below).
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EMC7 Antibody (F-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects EMC7 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EMC7 (F-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. EMC7 plays a crucial role in the endoplasmic reticulum (ER) and is involved in the regulation of protein quality control and the unfolded protein response, which are essential for maintaining cellular homeostasis and preventing stress-induced apoptosis. Dysregulation of these processes can lead to various diseases, including neurodegenerative disorders and cancer, highlighting the importance of studying EMC7 in both basic and translational research. Understanding EMC7 function can provide insights into its potential as a therapeutic target and role in cellular stress responses, making EMC7 (F-3) antibody a valuable tool for researchers investigating these critical biological pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
EMC7 Antibody (F-3) References:
- Analysis of the DNA sequence and duplication history of human chromosome 15. | Zody, MC., et al. 2006. Nature. 440: 671-5. PMID: 16572171
- Effective gene therapy in an authentic model of Tay-Sachs-related diseases. | Cachón-González, MB., et al. 2006. Proc Natl Acad Sci U S A. 103: 10373-10378. PMID: 16801539
- Pyrimethamine as a potential pharmacological chaperone for late-onset forms of GM2 gangliosidosis. | Maegawa, GH., et al. 2007. J Biol Chem. 282: 9150-61. PMID: 17237499
- Molecular epigenetics of Angelman syndrome. | Lalande, M. and Calciano, MA. 2007. Cell Mol Life Sci. 64: 947-60. PMID: 17347796
- [The Prader-Willi syndrome]. | Diene, G., et al. 2007. Ann Endocrinol (Paris). 68: 129-37. PMID: 17499572
- Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes. | Makoff, AJ. and Flomen, RH. 2007. Genome Biol. 8: R114. PMID: 17573966
- Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events. | Ramirez, F. and Dietz, HC. 2007. J Cell Physiol. 213: 326-30. PMID: 17708531
- Extracellular control of TGFbeta signalling in vascular development and disease. | ten Dijke, P. and Arthur, HM. 2007. Nat Rev Mol Cell Biol. 8: 857-69. PMID: 17895899
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EMC7 Antibody (F-3) | sc-514440 | 200 µg/ml | $316.00 | |||
EMC7 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-531127 | 200 µg Ab; 10 µg BP | $354.00 | |||
EMC7 Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-524726 | 200 µg Ab, 40 µg BP | $354.00 | |||
EMC7 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-544409 | 200 µg Ab; 20 µg BP | $354.00 | |||
EMC7 Antibody (F-3) AC | sc-514440 AC | 500 µg/ml, 25% agarose | $416.00 | |||
EMC7 Antibody (F-3) HRP | sc-514440 HRP | 200 µg/ml | $316.00 | |||
EMC7 Antibody (F-3) FITC | sc-514440 FITC | 200 µg/ml | $330.00 | |||
EMC7 Antibody (F-3) PE | sc-514440 PE | 200 µg/ml | $343.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 488 | sc-514440 AF488 | 200 µg/ml | $357.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 546 | sc-514440 AF546 | 200 µg/ml | $357.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 594 | sc-514440 AF594 | 200 µg/ml | $357.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 647 | sc-514440 AF647 | 200 µg/ml | $357.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 680 | sc-514440 AF680 | 200 µg/ml | $357.00 | |||
EMC7 Antibody (F-3) Alexa Fluor® 790 | sc-514440 AF790 | 200 µg/ml | $357.00 |