EB3 Antibody (KT36): sc-101475

EB3 Antibody (KT36) is a rat monoclonal IgG2a antibody that detects EB3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EB3 antibody (KT36) plays a crucial role in studying microtubule dynamics, as EB3 is a member of the microtubule-associated protein family and is essential for regulating microtubule growth and stability. EB3 is predominantly located at growing ends of microtubules, where EB3 facilitates recruitment of other proteins necessary for microtubule assembly and stabilization, which is vital for various cellular processes, including cell division and intracellular transport. EB3 function is particularly important in cancer biology, as dysregulation of microtubule dynamics can lead to abnormal cell proliferation and tumorigenesis. EB3 has been shown to interact with other proteins such as APC (adenomatous polyposis coli), a key tumor suppressor involved in colorectal cancer. This interaction between EB3 and APC highlights EB3′s significance in maintaining cellular homeostasis and potential role in cancer progression. With insights into microtubule behavior and implications in disease, EB3 (KT36) monoclonal antibody serves as an invaluable tool for researchers investigating molecular mechanisms underlying various pathologies.

The preferred EB3 antibody is EB3 Antibody (7): sc-136405.