EAP30 Antibody (H-3): sc-390748

EAP30 Antibody (H-3) is a mouse monoclonal IgG1 antibody that detects EAP30 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EAP30, also known as ELL-associated protein of 30 kDa, SNF8, Dot3, or VPS22, is a 258 amino acid protein that plays a crucial role in the endosomal sorting pathway. EAP30 is a key component of the ESCRT-II complex, which is essential for the formation of multivesicular bodies (MVBs) and the sorting of endosomal cargo proteins. Proper functioning of EAP30 is vital for cellular homeostasis, as EAP30 not only facilitates the degradation of proteins by targeting them to the lysosome but also regulates transcription by repressing RNA polymerase II activity. This dual functionality underscores the importance of EAP30 in maintaining cellular integrity and regulating gene expression, making EAP30 a significant target for research in cellular processes and disease mechanisms. Anti-EAP30 antibody (H-3) is an invaluable tool for scientists studying these critical pathways and their implications in various biological contexts.

The preferred EAP30 antibody is EAP30 Antibody (C-11): sc-390747.