EAG Antibody (C-7): sc-377446
- EAG Antibody (C-7) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 215-429 of EAG of Streptococcus equi subsp. equi origin
- recommended for detection of EAG of S. equi origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for EAG Antibody (C-7) for WB applications. This reagent is now offered in a bundle with EAG Antibody (C-7) (see ordering information below).
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EAG Antibody (C-7) is a mouse monoclonal IgG2b antibody that detects EAG protein of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EAG antibody (C-7) specifically targets EAG protein, which is a 429 amino acid molecule known for binding alpha2-macroglobulin and albumin, crucial for the pathogen′s ability to evade the host′s immune response. EAG protein′s function facilitates the survival of Streptococcus equi within the host, allowing bacteria to persist and cause the highly contagious disease known as strangles, which primarily affects young horses with underdeveloped immune systems. EAG presence in the pathogen contributes to the profound inflammatory response observed in infected horses, characterized by symptoms such as lymphadenopathy of the head and neck, fever, nasal discharge, and lack of appetite. EAG (C-7) antibody applications in research provide valuable insights into infection mechanisms and host-pathogen interactions that lead to clinical manifestations of strangles, ultimately aiding in the development of effective treatments and preventive measures.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EAG Antibody (C-7) | sc-377446 | 200 µg/ml | $316.00 | |||
EAG Antibody (C-7): m-IgG2b BP-HRP Bundle | sc-548609 | 200 µg Ab; 10 µg BP | $354.00 |