E-FABP Antibody (B-3): sc-365166

E-FABP Antibody (B-3) is a mouse monoclonal IgG1 antibody that detects E-FABP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). E-FABP, or epithelial fatty acid-binding protein, is a crucial member of the fatty acid-binding protein family, known for its role in binding stearic acid and involvement in keratinocyte differentiation. anti-E-FABP antibody (B-3) recognizes a protein predominantly expressed in the epidermis that plays a significant role in maintaining lipid homeostasis and cellular signaling within skin tissues. E-FABP′s ability to facilitate the uptake and transport of fatty acids is essential for various physiological processes, including the regulation of inflammation and response to injury. Notably, E-FABP expression is upregulated in rat dorsal root ganglia following sciatic nerve crush, indicating its potential role in neuronal differentiation and repair during development. E-FABP monoclonal antibody (B-3) serves as an invaluable tool for researchers investigating the intricate mechanisms of lipid metabolism and cellular differentiation in various biological contexts.

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E-FABP Antibody (B-3) References:

1. Probable interaction between S100A7 and E-FABP in the cytosol of human keratinocytes from psoriatic scales.  |  Hagens, G., et al. 1999. Mol Cell Biochem. 192: 123-8. PMID: 10331666
2. In situ and immunocytochemical localization of E-FABP mRNA and protein during neuronal migration and differentiation in the rat brain.  |  Liu, Y., et al. 2000. Brain Res. 852: 16-27. PMID: 10661491
3. Expression of E-FABP in PC12 cells increases neurite extension during differentiation: involvement of n-3 and n-6 fatty acids.  |  Liu, JW., et al. 2008. J Neurochem. 106: 2015-29. PMID: 18513372
4. E-FABP induces differentiation in normal human keratinocytes and modulates the differentiation process in psoriatic keratinocytes in vitro.  |  Dallaglio, K., et al. 2013. Exp Dermatol. 22: 255-61. PMID: 23528210
5. Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-β responses in tumor-associated macrophages.  |  Zhang, Y., et al. 2014. Cancer Res. 74: 2986-98. PMID: 24713431
6. Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice.  |  Bando, Y., et al. 2014. J Mol Histol. 45: 507-18. PMID: 24879443
7. Epidermal Fatty Acid Binding Protein (E-FABP) Is Not Required for the Generation or Maintenance of Effector and Memory T Cells following Infection with Listeria monocytogenes.  |  Li, B. and Schmidt, NW. 2016. PLoS One. 11: e0162427. PMID: 27588422
8. Retinoic acid regulates cell-shape and -death of E-FABP (FABP5)-immunoreactive septoclasts in the growth plate cartilage of mice.  |  Bando, Y., et al. 2017. Histochem Cell Biol. 148: 229-238. PMID: 28500502
9. Septoclasts expressing epidermal fatty acid-binding protein (E-FABP, FABP5) in endochondral ossification.  |  Bando, Y., et al. 2022. J Oral Biosci. 64: 18-25. PMID: 34915120
10. Salivary and Lacrimal Gland Alterations of the Epidermal Fatty Acid-Binding Protein (E-FABP) in Non-Obese Diabetic Mice.  |  Dogru, M., et al. 2022. Int J Mol Sci. 23: PMID: 35408851

The preferred E-FABP antibody is E-FABP Antibody (A-9): sc-365236.