DTX3L Antibody (45.Y): sc-100627
- DTX3L Antibody (45.Y) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 100 µg/ml
- raised against recombinant DTX3L of human origin
- recommended for detection of DTX3L of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DTX3L Antibody (45.Y). This work is in progress.
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SEE ALSO...
DTX3L Antibody (45.Y) is a mouse monoclonal IgG2a antibody that detects DTX3L in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). DTX3L, also known as BBAP, is a 740 amino acid protein that plays a crucial role in the ubiquitination pathway, functioning as a ubiquitin ligase in vitro. Anti-DTX3L antibody (45.Y) recognizes a protein structure featuring a basic N-terminus, a central proline-rich region, and a C-terminal RING-type zinc finger domain, which is essential for binding two zinc ions and forming a cross-brace motif. This structural motif is critical for the activity of many proteins involved in ubiquitin-protein isopeptide ligase functions, particularly in the regulation of protein degradation and signaling pathways. DTX3L′s ability to heterodimerize with Deltex-1 enhances the E3 ubiquitin ligase complex′s activity, thereby amplifying the influence of the Notch signaling pathway, which is vital for various cellular processes, including cell differentiation and development. DTX3L monoclonal antibody (45.Y) serves as an invaluable tool for researchers studying the intricacies of Notch signaling and its implications in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DTX3L Antibody (45.Y) | sc-100627 | 100 µg/ml | $333.00 |