DRAK2 Antibody (C-2): sc-398324
- DRAK2 Antibody (C-2) is a mouse monoclonal IgG1 κ DRAK2 antibody provided at 200 µg/ml
- raised against amino acids 256-372 mapping at the C-terminus of DRAK2 of human origin
- DRAK2 Antibody (C-2) is recommended for detection of DRAK2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-DRAK2 Antibody (C-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DRAK2 Antibody (C-2) for WB and IHC(P) applications. These reagents are now offered in bundles with DRAK2 Antibody (C-2) (see ordering information below).
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DRAK2 Antibody (C-2) is a mouse monoclonal IgG1 kappa light chain antibody that detects DRAK2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-DRAK2 antibody (C-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DRAK2 plays a crucial role in regulating apoptosis, which is essential for maintaining cellular homeostasis and preventing uncontrolled cell proliferation that can lead to cancer. DRAK2, along with related proteins DRAK1 and DAP kinase, is localized in the nucleus, where DRAK2 can influence apoptotic signaling pathways. DRAK2′s ability to mediate apoptosis is particularly important in cancer therapy, as enhancing apoptosis in tumor cells can improve treatment outcomes. DRAK2′s interactions with other proteins, such as DAP kinase and ZIP kinase, highlight DRAK2′s involvement in complex signaling networks that regulate cell death and survival. Using DRAK2 (C-2) monoclonal antibody in research can provide valuable insights into apoptosis mechanisms and potential therapeutic targets for cancer treatment.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
DRAK2 Antibody (C-2) References:
- Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. | Hai, TW., et al. 1989. Genes Dev. 3: 2083-90. PMID: 2516827
- Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. | Deiss, LP., et al. 1995. Genes Dev. 9: 15-30. PMID: 7828849
- DAP kinase links the control of apoptosis to metastasis. | Inbal, B., et al. 1997. Nature. 390: 180-4. PMID: 9367156
- ZIP kinase, a novel serine/threonine kinase which mediates apoptosis. | Kawai, T., et al. 1998. Mol Cell Biol. 18: 1642-51. PMID: 9488481
- Molecular cloning and developmental expression of a rat homologue of death-associated protein kinase in the nervous system. | Sakagami, H. and Kondo, H. 1997. Brain Res Mol Brain Res. 52: 249-56. PMID: 9495546
- DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis. | Sanjo, H., et al. 1998. J Biol Chem. 273: 29066-71. PMID: 9786912
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DRAK2 Antibody (C-2) | sc-398324 | 200 µg/ml | $316.00 | |||
DRAK2 Antibody (C-2): m-IgG Fc BP-HRP Bundle | sc-530760 | 200 µg Ab; 10 µg BP | $354.00 | |||
DRAK2 Antibody (C-2): m-IgGκ BP-HRP Bundle | sc-524295 | 200 µg Ab, 40 µg BP | $354.00 | |||
DRAK2 Antibody (C-2): m-IgG1 BP-HRP Bundle | sc-544240 | 200 µg Ab; 20 µg BP | $354.00 | |||
DRAK2 Antibody (C-2) AC | sc-398324 AC | 500 µg/ml, 25% agarose | $416.00 | |||
DRAK2 Antibody (C-2) HRP | sc-398324 HRP | 200 µg/ml | $316.00 | |||
DRAK2 Antibody (C-2) FITC | sc-398324 FITC | 200 µg/ml | $330.00 | |||
DRAK2 Antibody (C-2) PE | sc-398324 PE | 200 µg/ml | $343.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 488 | sc-398324 AF488 | 200 µg/ml | $357.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 546 | sc-398324 AF546 | 200 µg/ml | $357.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 594 | sc-398324 AF594 | 200 µg/ml | $357.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 647 | sc-398324 AF647 | 200 µg/ml | $357.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 680 | sc-398324 AF680 | 200 µg/ml | $357.00 | |||
DRAK2 Antibody (C-2) Alexa Fluor® 790 | sc-398324 AF790 | 200 µg/ml | $357.00 |