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DPF2 Antibody (WW-2) is a mouse monoclonal IgG2a antibody that detects DPF2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). DPF2, also known as REQ, UBID4, or ubi-d4, is a 391 amino acid protein belonging to the D4 domain family and is characterized by nuclear localization and the presence of one C2H2- and two PHD-type zinc finger motifs. DPF2 functions as a transcription factor essential for apoptosis, which is programmed cell death necessary for maintaining cellular homeostasis and eliminating damaged cells. LRF (Leukemia/lymphoma-related factor), a protein up-regulated by Integrin during apoptosis, can inhibit DPF2 activity. This interaction highlights DPF2′s potential as a therapeutic target in cancer treatments aimed at inducing apoptosis in leukemia cells, making DPF2 a valuable focus for research in cancer biology. Anti-DPF2 antibody (WW-2) serves as an essential tool for scientists investigating the mechanisms of apoptosis and the development of targeted cancer therapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DPF2 Antibody (WW-2) | sc-101106 | 100 µg/ml | $333.00 |