DNA pol δ 2 Antibody (2762C3a): sc-81250
- DNA pol δ 2 Antibody (2762C3a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to a region near the N-terminus of DNA pol δ 2 of human origin
- recommended for detection of DNA pol δ 2 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DNA pol δ 2 Antibody (2762C3a). This work is in progress.
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DNA pol δ 2 Antibody (2762C3a) is a mouse monoclonal IgG1 antibody that detects DNA polymerase delta (DNA pol δ) in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). DNA pol δ plays a crucial role in DNA replication, particularly in the processing of Okazaki fragments on the lagging strand, which is essential for maintaining genome stability. DNA pol δ is composed of two main subunits, p125 and p50, with p125 directly interacting with the sliding DNA clamp protein PCNA, facilitating efficient DNA synthesis. DNA pol δ is subject to regulation by various cell cycle proteins, ensuring that activity is appropriately timed during cell division. Understanding the function and regulation of DNA pol δ is vital, as any dysregulation can lead to genomic instability and contribute to the development of various diseases, including cancer. Anti-DNA pol δ antibody (2762C3a) is an invaluable tool for researchers studying the mechanisms of DNA replication and repair, providing insights into the intricate processes that safeguard genetic information.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DNA pol δ 2 Antibody (2762C3a) | sc-81250 | 100 µg/ml | $333.00 |