


DGK-θ Antibody (24) is a mouse monoclonal IgG1 antibody that detects diacylglycerol kinase theta (DGK-θ) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). DGK-θ plays a crucial role in lipid signaling by phosphorylating diacylglycerol to generate phosphatidic acid, a key second messenger involved in various cellular processes, including cell proliferation, differentiation, and survival. DGK-θ modulates signaling pathways that influence cellular responses to external stimuli, thereby impacting processes such as immune response and neuronal signaling. DGK-θ is predominantly expressed in the cerebellum and hippocampus, regions critical for motor control and memory formation, respectively. This localization underscores DGK-θ′s potential significance in neurodevelopmental and neurodegenerative disorders. The DGK family, including DGK-θ, is characterized by distinct structural motifs that dictate regulatory functions, and understanding these interactions can provide insights into therapeutic targets for diseases associated with dysregulated lipid signaling. Anti-DGK-θ antibody (24) serves as an essential tool for researchers investigating the intricate roles of diacylglycerol kinases in cellular signaling and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DGK-θ Antibody (24) | sc-135882 | 50 µg/0.5 ml | $322.00 |