DGK Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calphostin C | 121263-19-2 | sc-3545 sc-3545A | 100 µg 1 mg | $336.00 $1642.00 | 20 | |
Calphostin C functions as a diacylglycerol kinase (DGK), exhibiting a remarkable affinity for diacylglycerol substrates. Its unique binding site facilitates specific phosphorylation, modulating lipid signaling pathways. The compound's stereochemistry contributes to its selectivity, influencing downstream cellular responses. Furthermore, Calphostin C's ability to alter membrane fluidity enhances its interaction with various lipid environments, impacting cellular signaling cascades and metabolic processes. | ||||||
R 59-022 | 93076-89-2 | sc-203227 | 5 mg | $122.00 | 1 | |
R 59-022 acts as a diacylglycerol kinase (DGK) with a distinctive mechanism of action, characterized by its rapid kinetics in phosphorylating diacylglycerol. Its structural conformation allows for selective interactions with lipid bilayers, promoting unique conformational changes that influence membrane dynamics. Additionally, R 59-022's ability to modulate enzyme activity through competitive inhibition highlights its role in fine-tuning lipid-mediated signaling pathways, impacting cellular homeostasis. | ||||||
Dioctanoylglycol | 627-86-1 | sc-203567 | 50 mg | $132.00 | ||
Dioctanoylglycol functions as a diacylglycerol kinase (DGK) with a unique ability to engage in specific lipid interactions, enhancing its affinity for membrane-associated substrates. Its hydrophobic nature facilitates integration into lipid bilayers, where it can influence membrane fluidity and organization. The compound exhibits distinct reaction kinetics, allowing for efficient phosphorylation of diacylglycerol, thereby playing a critical role in regulating lipid signaling cascades and cellular energy balance. | ||||||
DAG Kinase Inhibitor II | 120166-69-0 | sc-3551 sc-3551A | 5 mg 25 mg | $135.00 $380.00 | 1 | |
DAG Kinase Inhibitor II acts as a selective modulator of diacylglycerol kinase activity, exhibiting a unique capacity to disrupt lipid-mediated signaling pathways. Its structural conformation allows for specific binding interactions with the enzyme's active site, effectively altering substrate accessibility. This compound demonstrates notable selectivity in inhibiting DGK isoforms, influencing downstream signaling events and cellular responses through its kinetic profile and interaction dynamics. | ||||||
Cochlioquinone A | 32450-25-2 | sc-202109 | 500 µg | $291.00 | 1 | |
Cochlioquinone A functions as a diacylglycerol kinase (DGK) modulator, characterized by its ability to engage in specific molecular interactions that influence lipid metabolism. Its unique structural features facilitate selective binding to DGK isoforms, impacting the enzyme's catalytic efficiency. The compound's kinetic behavior reveals a distinct inhibition pattern, altering the dynamics of lipid signaling pathways and contributing to the regulation of cellular processes through its interaction with membrane-associated lipids. | ||||||