


DGK-ι Antibody (D-4) is a mouse monoclonal IgM antibody that detects diacylglycerol kinase iota (DGK-ι) in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DGK-ι plays a crucial role in lipid signaling by phosphorylating diacylglycerol to generate phosphatidic acid, a key second messenger involved in numerous cellular processes such as cell proliferation, differentiation, and survival. DGK-ι (D-4) antibody helps researchers study signaling pathways that influence cell fate decisions, particularly in neuronal function and development, where DGK-ι is predominantly expressed in the brain and retina. This expression pattern suggests DGK-ι may be integral to the regulation of synaptic signaling and plasticity, which are vital for learning and memory. Additionally, DGK-ι is characterized by specific structural motifs that contribute to regulatory functions, allowing for the fine-tuning of lipid-mediated signaling cascades. With diverse applications and significant role in cellular signaling, anti-DGK-ι antibody (D-4) serves as an essential tool for investigating the complexities of lipid signaling in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DGK-ι Antibody (D-4) | sc-271383 | 200 µg/ml | $322.00 |