DGCR14 Antibody (2264C3a): sc-81079
- DGCR14 Antibody (2264C3a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of DGCR14 of human origin
- recommended for detection of DGCR14 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DGCR14 Antibody (2264C3a). This work is in progress.
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DGCR14 Antibody (2264C3a) is a mouse monoclonal IgG1 antibody that detects DGCR14 in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). DGCR14 is a 476 amino acid nuclear protein that is part of the DGCR14 family and plays a crucial role in the etiology of velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder associated with various structural and functional anomalies, including palate defects, conotruncal cardiac malformations, immunodeficiency, and characteristic facial features. DGCR14 is primarily located in the nucleus, where DGCR14 co-purifies with C complex spliceosomes, highlighting a potential role in RNA processing and gene regulation. The interaction of DGCR14 with spliceosomal components is vital for the proper splicing of pre-mRNA, which is essential for the production of functional proteins. Disruptions in this process can lead to a range of developmental and health issues, making DGCR14 a significant protein for research in developmental biology and genetic disorders. Anti-DGCR14 antibody (2264C3a) is an invaluable tool for researchers investigating the molecular mechanisms underlying these conditions and the broader implications of RNA processing in cellular function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DGCR14 Antibody (2264C3a) | sc-81079 | 100 µg/ml | $339.00 |