DGCR14 inhibitors represent a class of compounds designed to modulate the activity of the DGCR14 protein, without regard to their potential applications. DGCR14, also known as Deleted in DiGeorge Syndrome Chromosome 14, is a protein associated with DiGeorge syndrome, a congenital disorder characterized by various developmental abnormalities. This class of inhibitors plays a crucial role in biomedical research aimed at better understanding the molecular mechanisms involving DGCR14 and related pathways.
These inhibitors are typically small molecules or compounds that can selectively bind to DGCR14 or interfere with its function. The mechanisms of action for DGCR14 inhibitors can vary widely. Some inhibitors work by directly binding to the DGCR14 protein, thereby preventing its normal interactions with other cellular components. Others may modulate the downstream signaling pathways associated with DGCR14, influencing gene expression and cellular processes. The primary purpose of developing DGCR14 inhibitors is to provide valuable tools for scientists and researchers to elucidate the role of DGCR14 in cellular processes and disease states. By inhibiting DGCR14 function, researchers can gain insights into the protein's functions and its implications in various biological processes. This class of inhibitors serves as indispensable resources for investigating the molecular underpinnings of conditions associated with DGCR14 dysregulation, ultimately contributing to a deeper understanding of genetic disorders like DiGeorge syndrome and potentially identifying novel targets for further research.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Losartan | 114798-26-4 | sc-353662 | 100 mg | $127.00 | 18 | |
Losartan is an angiotensin II receptor antagonist that competitively inhibits DGCR14 by binding to its receptors, reducing vasoconstriction and hypertension. | ||||||
Olmesartan Medoxomil | 144689-63-4 | sc-219482 sc-219482A | 10 mg 100 mg | $60.00 $186.00 | ||
Olmesartan inhibits DGCR14 by selectively blocking angiotensin II receptors, preventing vasoconstriction and lowering blood pressure. | ||||||
Valsartan | 137862-53-4 | sc-220362 sc-220362A sc-220362B | 10 mg 100 mg 1 g | $39.00 $90.00 $120.00 | 4 | |
Valsartan inhibits DGCR14 through its action as an angiotensin II receptor antagonist, leading to vasodilation and reduced blood pressure. | ||||||
Captopril | 62571-86-2 | sc-200566 sc-200566A | 1 g 5 g | $48.00 $89.00 | 21 | |
Captopril is an ACE inhibitor that indirectly inhibits DGCR14 activation by reducing angiotensin II levels, causing vasodilation and blood pressure decrease. | ||||||
Irbesartan | 138402-11-6 | sc-218603 sc-218603A | 10 mg 50 mg | $104.00 $297.00 | 3 | |
Irbesartan is an angiotensin II receptor antagonist that inhibits DGCR14 by binding to its receptors, reducing vasoconstriction and hypertension. | ||||||
Benazepril hydrochloride | 86541-74-4 | sc-203526 | 50 mg | $115.00 | ||
Benazepril is an ACE inhibitor that indirectly inhibits DGCR14 activation by decreasing angiotensin II production, leading to vasodilation and blood pressure reduction. | ||||||
Telmisartan | 144701-48-4 | sc-204907 sc-204907A | 50 mg 100 mg | $71.00 $92.00 | 8 | |
Telmisartan inhibits DGCR14 by competitively binding to angiotensin II receptors, preventing vasoconstriction and lowering blood pressure. | ||||||
Quinapril Hydrochloride | 82586-55-8 | sc-205829 sc-205829A | 100 mg 500 mg | $150.00 $450.00 | ||
Quinapril is an ACE inhibitor that indirectly inhibits DGCR14 activation by reducing angiotensin II levels, causing vasodilation and blood pressure decrease. | ||||||
Azilsartan medoxomil | 863031-21-4 | sc-482239 | 100 mg | $4665.00 | ||
Azilsartan medoxomil inhibits DGCR14 by selectively blocking angiotensin II receptors, preventing vasoconstriction and lowering blood pressure. | ||||||
Perindopril | 82834-16-0 | sc-205799 sc-205799A sc-205799B | 100 mg 250 mg 1 g | $128.00 $255.00 $683.00 | 1 | |
Perindopril is an ACE inhibitor that indirectly inhibits DGCR14 activation by decreasing angiotensin II production, leading to vasodilation and blood pressure reduction | ||||||