DDX59 Antibody (C-3): sc-514439
- DDX59 Antibody (C-3) is a mouse monoclonal IgG1 κ DDX59 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-22 at the N-terminus of DDX59 of human origin
- DDX59 Antibody (C-3) is recommended for detection of DDX59 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-DDX59 Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DDX59 Antibody (C-3) for WB applications. These reagents are now offered in bundles with DDX59 Antibody (C-3) (see ordering information below).
DDX59 Antibody (C-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects DDX59 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDX59 (C-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DDX59, also known as zinc finger HIT domain-containing protein 5, is a 619 amino acid protein that plays a crucial role in RNA metabolism, particularly in the assembly and function of ribonucleoprotein complexes. DDX59 is characterized by a unique structure, which includes a helicase C-terminal domain and a HIT-type zinc finger, allowing DDX59 to interact with RNA and other proteins effectively. A Q motif within DDX59 is essential for ATP binding and hydrolysis, which are critical for helicase activity. DDX59 functions are vital for various cellular processes, including embryogenesis and cellular growth, making DDX59 an important target for research in developmental biology and cancer studies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
DDX59 Antibody (C-3) References:
- Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. | Simpson, JC., et al. 2000. EMBO Rep. 1: 287-92. PMID: 11256614
- DExD/H box RNA helicases: from generic motors to specific dissociation functions. | Tanner, NK. and Linder, P. 2001. Mol Cell. 8: 251-62. PMID: 11545728
- Identification of a novel human DDX40gene, a new member of the DEAH-box protein family. | Xu, J., et al. 2002. J Hum Genet. 47: 681-3. PMID: 12522690
- The human DDX and DHX gene families of putative RNA helicases. | Abdelhaleem, M., et al. 2003. Genomics. 81: 618-22. PMID: 12782131
- D-E-A-D protein family of putative RNA helicases. | Schmid, SR. and Linder, P. 1992. Mol Microbiol. 6: 283-91. PMID: 1552844
- The DEAD-box protein family of RNA helicases. | Cordin, O., et al. 2006. Gene. 367: 17-37. PMID: 16337753
- Dead-box proteins: a family affair--active and passive players in RNP-remodeling. | Linder, P. 2006. Nucleic Acids Res. 34: 4168-80. PMID: 16936318
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDX59 Antibody (C-3) | sc-514439 | 200 µg/ml | $322.00 | |||
DDX59 Antibody (C-3): m-IgG Fc BP-HRP Bundle | sc-531126 | 200 µg Ab; 10 µg BP | $361.00 | |||
DDX59 Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-524725 | 200 µg Ab, 40 µg BP | $361.00 | |||
DDX59 Antibody (C-3): m-IgG1 BP-HRP Bundle | sc-544408 | 200 µg Ab; 20 µg BP | $361.00 | |||
DDX59 Antibody (C-3) AC | sc-514439 AC | 500 µg/ml, 25% agarose | $424.00 | |||
DDX59 Antibody (C-3) HRP | sc-514439 HRP | 200 µg/ml | $322.00 | |||
DDX59 Antibody (C-3) FITC | sc-514439 FITC | 200 µg/ml | $336.00 | |||
DDX59 Antibody (C-3) PE | sc-514439 PE | 200 µg/ml | $349.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 488 | sc-514439 AF488 | 200 µg/ml | $364.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 546 | sc-514439 AF546 | 200 µg/ml | $364.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 594 | sc-514439 AF594 | 200 µg/ml | $364.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 647 | sc-514439 AF647 | 200 µg/ml | $364.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 680 | sc-514439 AF680 | 200 µg/ml | $364.00 | |||
DDX59 Antibody (C-3) Alexa Fluor® 790 | sc-514439 AF790 | 200 µg/ml | $364.00 | |||
DDX59 (C-3) Neutralizing Peptide | sc-514439 P | 100 µg/0.5 ml | $69.00 |