DDX11 Antibody (C-10): sc-515166
- DDX11 Antibody (C-10) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 71-89 near the N-terminus of DDX11 of human origin
- recommended for detection of DDX11 and DDX12 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DDX11 Antibody (C-10) for WB applications. These reagents are now offered in bundles with DDX11 Antibody (C-10) (see ordering information below).
DDX11 Antibody (C-10) is a mouse monoclonal IgG2b antibody that detects DDX11 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDX11, also known as CHLR1 or KRG2, is a crucial member of the DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp motif, and is known for dual ATPase and DNA helicase activities. DDX11 plays a vital role in maintaining genomic stability, as DDX11 is essential for proper chromosome segregation during cell division and is involved in embryonic development. DDX11 is predominantly localized in the nucleus and exhibits high expression levels in the testis, thymus, ovary, spleen, and pancreas, highlighting DDX11′s importance in reproductive and immune functions. Notably, DDX11 can interact with both single- and double-stranded DNA, facilitating essential processes such as ribosome and spliceosome assembly, which are critical for RNA modifications and overall cellular function. Additionally, the existence of five isoforms of DDX11, resulting from alternative splicing, suggests a complex regulatory mechanism that may allow for diverse functional roles in various cellular contexts. Anti-DDX11 antibody (C-10) is an invaluable tool for researchers studying the intricate dynamics of RNA processing and chromosomal integrity in human cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDX11 Antibody (C-10) | sc-515166 | 200 µg/ml | $322.00 | |||
DDX11 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-538752 | 200 µg Ab; 10 µg BP | $361.00 | |||
DDX11 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-536420 | 200 µg Ab; 40 µg BP | $361.00 | |||
DDX11 (C-10) Neutralizing Peptide | sc-515166 P | 100 µg/0.5 ml | $69.00 |