DDO Antibody (D-8): sc-376705
- DDO Antibody (D-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 153-192 mapping within an internal region of DDO of mouse origin
- recommended for detection of DDO of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for DDO Antibody (D-8) for WB applications. This reagent is now offered in a bundle with DDO Antibody (D-8) (see ordering information below).
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SEE ALSO...
DDO Antibody (D-8) is a mouse monoclonal IgG2b antibody that detects D-aspartate oxidase (DDO) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDO is a 341 amino acid protein that plays a crucial role in the oxidative deamination of D-aspartate and N-methyl D-aspartate, utilizing flavin adenine dinucleotide or 6-hydroxyflavin adenine dinucleotide as cofactors. This enzymatic activity is vital for regulating neurotransmitter levels and metabolic processes in the brain, highlighting DDO′s importance in neurobiology and potential implications in neurological disorders. DDO localizes to peroxisomes and exists in two alternatively spliced isoforms, DDO-1 and DDO-2, which may have distinct functional roles. The gene encoding DDO is located on human chromosome 6, a region associated with various diseases, including early onset intestinal cancer and several neuropsychiatric disorders, indicating DDO′s broader implications in health and disease. Anti-DDO antibody (D-8) serves as an essential tool for researchers investigating the functional dynamics of D-aspartate oxidase and its involvement in critical biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DDO Antibody (D-8) | sc-376705 | 200 µg/ml | $322.00 | |||
DDO Antibody (D-8): m-IgG2b BP-HRP Bundle | sc-548603 | 200 µg Ab; 10 µg BP | $361.00 |