Date published: 2025-9-20

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Cytokeratin 23 Antibody (14L-3): sc-100927

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Datasheets
  • Cytokeratin 23 Antibody (14L-3) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
  • raised against recombinant Cytokeratin 23 of human origin
  • recommended for detection of Cytokeratin 23 of human origin by WB, IP, IF, IHC(P) and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cytokeratin 23 Antibody (14L-3). This work is in progress.

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    Cytokeratin 23 Antibody (14L-3) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 23 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Cytokeratin 23, also known as KRT23, K23, CK23, or HAIK1, is a 422 amino acid intermediate filament protein that forms a heterotetramer composed of two type I and two type II Cytokeratins, playing a vital role in maintaining the structural integrity of epithelial cells. Cytokeratin 23 is predominantly located in the cytoplasm of epithelial cells, where Cytokeratin 23 contributes to the mechanical resilience of tissues, making Cytokeratin 23 essential for cellular stability and function. Notably, Cytokeratin 23 expression is upregulated in pancreatic cancer cells, indicating Cytokeratin 23′s potential involvement in carcinogenesis and tumor progression. Anti-Cytokeratin 23 antibody (14L-3) effectively detects Cytokeratin 23 in various applications, making anti-Cytokeratin 23 antibody (14L-3) a valuable tool for researchers studying epithelial cell biology and cancer pathology.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Cytokeratin 23 Antibody (14L-3)

    sc-100927
    100 µg/ml
    $333.00

    Can sc-100927: Cytokeratin 23 (14L-3) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: Professor Griffin
    Thank you for your question. Yes, sc-100927: Cytokeratin 23 (14L-3) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 4 out of 5 by from Good nuclear and cytoplasmic staining withGood nuclear and cytoplasmic staining with paraffin-embedded human ovarian cancer. -SCBT QC
    Date published: 2015-03-24
    Rated 3 out of 5 by from IF: nuclear staining in HeLa samplesIF: nuclear staining in HeLa samples. -SCBT QC
    Date published: 2015-03-17
    Rated 3 out of 5 by from Positive WB data in HeLa samplesPositive WB data in HeLa samples. -SCBT QC
    Date published: 2015-02-11
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    Cytokeratin 23 Antibody (14L-3) is rated 3.3 out of 5 by 3.
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