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Cytokeratin 23 Antibody (14L-3) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 23 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Cytokeratin 23, also known as KRT23, K23, CK23, or HAIK1, is a 422 amino acid intermediate filament protein that forms a heterotetramer composed of two type I and two type II Cytokeratins, playing a vital role in maintaining the structural integrity of epithelial cells. Cytokeratin 23 is predominantly located in the cytoplasm of epithelial cells, where Cytokeratin 23 contributes to the mechanical resilience of tissues, making Cytokeratin 23 essential for cellular stability and function. Notably, Cytokeratin 23 expression is upregulated in pancreatic cancer cells, indicating Cytokeratin 23′s potential involvement in carcinogenesis and tumor progression. Anti-Cytokeratin 23 antibody (14L-3) effectively detects Cytokeratin 23 in various applications, making anti-Cytokeratin 23 antibody (14L-3) a valuable tool for researchers studying epithelial cell biology and cancer pathology.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 23 Antibody (14L-3) | sc-100927 | 100 µg/ml | $333.00 |