Cytokeratin 19 Antibody (F-6): sc-374386

Cytokeratin 19 Antibody (F-6) is a mouse monoclonal IgM kappa light chain antibody designed to detect Cytokeratin 19, also known as KRT19, an important intermediate filament protein found in epithelial cells. Cytokeratin 19 plays a critical role in maintaining the structural integrity and resilience of epithelial tissues by forming filamentous networks through interactions with other cytokeratins, such as KRT8, as well as with proteins like plectin and desmoplakin that link the cytoskeleton to cellular junctions. Anti-Cytokeratin 19 antibody (F-6) targets a specific epitope between amino acids 7-29 at the N-terminus of Cytokeratin 19, ensuring effective recognition in mouse, rat, and human samples, as well as additional species including equine and porcine, across various applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). The interactions of Cytokeratin 19 with these proteins are essential for cellular stability, signal transduction, and the dynamic remodeling of the cytoskeleton during processes like cell migration and division. Cytokeratin 19 (F-6) antibody facilitates the study of epithelial cell behavior in both normal physiology and pathological conditions, including cancer, where Cytokeratin 19 serves as a valuable biomarker for tumor differentiation and progression. Available in a non-conjugated form, Cytokeratin 19 monoclonal antibody (F-6) provides researchers with the flexibility to employ various experimental setups, enabling precise detection and analysis of Cytokeratin 19 and its interactions. Anti-Cytokeratin 19 antibody (F-6) serves as an indispensable tool for advancing cancer diagnostics, understanding epithelial biology, and exploring the molecular mechanisms underlying tumor development and metastasis.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Cytokeratin 19 Antibody (F-6) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Cytokeratin 19 Antibody (F-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Cytokeratin 19 Antibody (F-6) Specifications

Alternate Product Name: KRT19

Product Clone Name: F-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 7-29

Epitope Target: Cytokeratin 19

Epitope Species: human

Product Reactivity/Detection: Cytokeratin 19

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Cytokeratin 19 Antibody (F-6): P: Blocking Peptide

The preferred Cytokeratin 19 antibody is Cytokeratin 19 Antibody (A-3): sc-376126.