Cytokeratin 19 Antibody (BA17): sc-53258

Cytokeratin 19 Antibody (BA17) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 19 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Cytokeratin 19 is a vital component of the cytoskeletal framework in epithelial cells, playing a crucial role in maintaining cellular integrity and providing mechanical support. Anti-Cytokeratin 19 antibody (BA17) expression is particularly significant in epithelial differentiation and tissue specialization, making Cytokeratin 19 an important marker for various pathological conditions, including cancer. Notably, Cytokeratin 19 is often upregulated in malignant tumors, serving as a specific marker for moderate to severe dysplasia and carcinoma in situ, especially within the oral cavity squamous epithelium. Cytokeratin 19 fragments in serum have been associated with lung cancer, and clinical studies have indicated that CYFRA 21-1, a fragment of Cytokeratin 19, may be one of the most reliable tumor markers for diagnosing hepatoma. Cytokeratin 19 monoclonal antibody (BA17) effectively identifies this marker across different species and applications, making Cytokeratin 19 (BA17) antibody an invaluable tool for researchers and clinicians aiming to understand and diagnose epithelial-related diseases.

The preferred Cytokeratin 19 antibody is Cytokeratin 19 Antibody (A-3): sc-376126.