cytochrome c Antibody (7H8): sc-13560
- cytochrome c Antibody (7H8) is a mouse monoclonal IgG2b κ, cited in 267 publications, provided at 200 µg/ml
- raised against full length denatured cytochrome c of human origin
- Anti-cytochrome c Antibody (7H8) is recommended for detection of cytochrome c of mouse, rat, human, equine and avian origin by WB, IP, IF and IHC(P)
- cytochrome c Antibody (7H8) is available conjugated to agarose (sc-13560 AC), 500 µg/ml, 25% agarose, for IP; and to either phycoerythrin (sc-13560 PE) or FITC (sc-13560 FITC), 200 µg/ml, for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for cytochrome c Antibody (7H8) for WB and IHC(P) applications. These reagents are now offered in bundles with cytochrome c Antibody (7H8) (see ordering information below).
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Cytochrome c Antibody (7H8) is a mouse monoclonal IgG2b kappa light chain antibody raised against full-length denatured human cytochrome c, reacting with mouse, rat, human, equine, and avian species. Cytochrome c, also known as CYC or CYCS, is a small heme protein located in the mitochondrial intermembrane space. A heme group covalently attached to a polypeptide chain forms a compact globular protein essential for function. This structure enables cytochrome c to transfer electrons between Complex III (cytochrome bc1 complex) and Complex IV (cytochrome c oxidase) in the electron transport chain, vital for ATP production during oxidative phosphorylation. Cytochrome c interacts with apoptotic protease activating factor-1 (Apaf-1) upon release into the cytosol, leading to apoptosome formation and activation of caspase-9 and caspase-3 in the intrinsic pathway of apoptosis. Understanding cytochrome c structural features is important because alterations can impact roles in both energy metabolism and programmed cell death. Cytochrome c (7H8) monoclonal antibody is suitable for applications such as western blotting, immunofluorescence, immunoprecipitation, and immunohistochemistry on paraffin-embedded sections. Cytochrome c antibody (7H8) enables researchers to study mitochondrial function, apoptosis mechanisms, and related cellular processes critical for insights into various physiological and pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cytochrome c Antibody (7H8) | sc-13560 | 200 µg/ml | $322.00 | |||
cytochrome c Antibody (7H8): m-IgG Fc BP-HRP Bundle | sc-525480 | 200 µg Ab; 10 µg BP | $361.00 | |||
cytochrome c Antibody (7H8): m-IgG2b BP-HRP Bundle | sc-549566 | 200 µg Ab; 10 µg BP | $361.00 | |||
cytochrome c Antibody (7H8) AC | sc-13560 AC | 500 µg/ml, 25% agarose | $424.00 | |||
cytochrome c Antibody (7H8) FITC | sc-13560 FITC | 200 µg/ml | $336.00 | |||
cytochrome c Antibody (7H8) PE | sc-13560 PE | 200 µg/ml | $349.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 488 | sc-13560 AF488 | 200 µg/ml | $364.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 546 | sc-13560 AF546 | 200 µg/ml | $364.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 594 | sc-13560 AF594 | 200 µg/ml | $364.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 647 | sc-13560 AF647 | 200 µg/ml | $364.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 680 | sc-13560 AF680 | 200 µg/ml | $364.00 | |||
cytochrome c Antibody (7H8) Alexa Fluor® 790 | sc-13560 AF790 | 200 µg/ml | $364.00 |