cytochrome b5 type B Antibody (F-5): sc-390876
- cytochrome b5 type B Antibody (F-5) is a mouse monoclonal IgG1 κ cytochrome b5 type B antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 86-130 mapping near the C-terminus of cytochrome b5 type B of human origin
- cytochrome b5 type B Antibody (F-5) is recommended for detection of cytochrome b5 type B of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-cytochrome b5 type B Antibody (F-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for cytochrome b5 type B Antibody (F-5) for WB and IHC(P) applications. These reagents are now offered in bundles with cytochrome b5 type B Antibody (F-5) (see ordering information below).
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Cytochrome b5 type B Antibody (F-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects cytochrome b5 type B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-cytochrome b5 type B antibody (F-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cytochrome b5 type B, also known as OMB5 or CYB5-M, is a 146 amino acid membrane-bound hemoprotein that plays a crucial role as an electron carrier for several membrane-bound oxygenases, facilitating essential biochemical reactions in cellular metabolism. Cytochrome b5 type B is primarily located in the outer mitochondrial membrane, where presence is vital for proper functioning of various enzymatic processes, including fatty acid desaturation and drug metabolism. Cytochrome b5 type B localization in the outer mitochondrial membrane underscores importance in maintaining mitochondrial function and energy production, as well as involvement in regulation of metabolic pathways critical for cellular homeostasis. Cytochrome b5 type B is encoded by a gene located on human chromosome 16q22.1, a region associated with several genetic disorders, highlighting potential implications of dysfunction in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
cytochrome b5 type B Antibody (F-5) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17. | Soucy, P. and Luu-The, V. 2002. J Steroid Biochem Mol Biol. 80: 71-5. PMID: 11867265
- Giant axonal neuropathy (GAN): case report and two novel mutations in the gigaxonin gene. | Kuhlenbäumer, G., et al. 2002. Neurology. 58: 1273-6. PMID: 11971098
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Advances in the genetics of inflammatory bowel disease. | Cho, JH. 2004. Curr Gastroenterol Rep. 6: 467-73. PMID: 15527676
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cytochrome b5 type B Antibody (F-5) | sc-390876 | 200 µg/ml | $322.00 | |||
cytochrome b5 type B Antibody (F-5): m-IgG Fc BP-HRP Bundle | sc-527652 | 200 µg Ab; 10 µg BP | $361.00 | |||
cytochrome b5 type B Antibody (F-5): m-IgG1 BP-HRP Bundle | sc-533025 | 200 µg Ab; 20 µg BP | $361.00 | |||
cytochrome b5 type B Antibody (F-5) AC | sc-390876 AC | 500 µg/ml, 25% agarose | $424.00 | |||
cytochrome b5 type B Antibody (F-5) HRP | sc-390876 HRP | 200 µg/ml | $322.00 | |||
cytochrome b5 type B Antibody (F-5) FITC | sc-390876 FITC | 200 µg/ml | $336.00 | |||
cytochrome b5 type B Antibody (F-5) PE | sc-390876 PE | 200 µg/ml | $349.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 488 | sc-390876 AF488 | 200 µg/ml | $364.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 546 | sc-390876 AF546 | 200 µg/ml | $364.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 594 | sc-390876 AF594 | 200 µg/ml | $364.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 647 | sc-390876 AF647 | 200 µg/ml | $364.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 680 | sc-390876 AF680 | 200 µg/ml | $364.00 | |||
cytochrome b5 type B Antibody (F-5) Alexa Fluor® 790 | sc-390876 AF790 | 200 µg/ml | $364.00 |