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Cyr61 Antibody (H-2) is a mouse monoclonal IgG1 antibody that detects Cyr61 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cyr61 is a secreted heparin-binding protein that plays a crucial role in various biological processes, including angiogenesis and tissue repair. As a member of the CCN protein family, which also includes connective tissue growth factor (CTGF), Cyr61 is vital for cell adhesion and migration, particularly in vascular endothelial cells, where Cyr61 binds to the Integrin αV/β3 receptor. This interaction not only stimulates DNA synthesis but also enhances cell motility, making Cyr61 essential for processes like wound healing and the formation of new blood vessels. Expression of Cyr61 is upregulated during these physiological events, and Cyr61 has been implicated in tumor biology, as Cyr61 is often found in elevated levels in various tumors, serving as a marker for tumor progression. The ability of Cyr61 to influence both normal and pathological processes underscores its significance in research and potential therapeutic applications, making anti-Cyr61 antibody (H-2) an invaluable tool for studying this multifaceted protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cyr61/CCN1 Antibody (H-2) | sc-271217 | 200 µg/ml | $316.00 | |||
Cyr61/CCN1 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-537590 | 200 µg Ab; 10 µg BP | $354.00 | |||
Cyr61/CCN1 Antibody (H-2): m-IgGκ BP-HRP Bundle | sc-534898 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cyr61/CCN1 Antibody (H-2): m-IgG1 BP-HRP Bundle | sc-545248 | 200 µg Ab; 20 µg BP | $354.00 | |||
Cyr61/CCN1 (H-2) Neutralizing Peptide | sc-271217 P | 100 µg/0.5 ml | $68.00 |